173034-99-6

Basic information

• Product Name: 4-((trimethylacetyl)oxy)aniline
• Synonyms: 4-((trimethylacetyl)oxy)aniline
• CAS NO: 173034-99-6
• Molecular Weight: 193.246
• Mol File: 173034-99-6.mol

Chemical Properties

• CAS DataBase Reference: 4-((trimethylacetyl)oxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((trimethylacetyl)oxy)aniline(173034-99-6)
• EPA Substance Registry System: 4-((trimethylacetyl)oxy)aniline(173034-99-6)

Safety Data

• Hazardous Substances Data: 173034-99-6(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 4195-17-9 4-nitrophenyl pivalate 
• 123-30-8 4-amino-phenol 
• 138459-91-3 3-pivaloyl-1,3-thiazolidine-2-thione 

Relevant articles and documents

Enantioselective, Lewis Base-Catalyzed, Intermolecular Sulfenoamination of Alkenes

A method for the catalytic, enantioselective, intermolecular, 1,2-sulfenoamination of alkenes is described. Functionalization is achieved through the intermediacy of an enantioenriched, configurationally stable thiiranium ion generated by Lewis base activation of a readily available sulfur electrophile. A diverse set of anilines and benzylamines react with different styrenes to afford products in good yield and stereoselectivity. Downstream manipulation of the products is facilitated by deprotonation of the amines to enable carbon-sulfur bond cleavage.

Highly chemoselective acylation of substituted aminophenols with 3-(trimethylacetyl)-1,3-thiazolidine-2-thione

A general procedure for chemoselective acylation of substituted aminophenols has been developed. The N-acetylated products 7 and 10a-h were prepared by treating the aminophenols with 3-(trimethylacetyl)-1,3-thiazolidine-2-thione (1) in refluxing THF in 70-100% yield. The esters 8 and 13d,b,j of 3- and 4-amino phenols could be obtained in 70-94% yield by treating with NaH and 1.