17309-13-6

Basic information

• Product Name: ethyl 4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate
• Synonyms: 5-thiazolecarboxylic acid, 2-mercapto-4-methyl-, ethyl ester; Ethyl 4-methyl-2-sulfanyl-1,3-thiazole-5-carboxylate
• CAS NO: 17309-13-6
• Molecular Formula: C₇H₉NO₂S₂
• Molecular Weight: 203.2819
• Mol File: 17309-13-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 295.2°C at 760 mmHg
• Flash Point: 132.3°C
• Density: 1.35g/cm³
• Vapor Pressure: 0.00155mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: ethyl 4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate(17309-13-6)
• EPA Substance Registry System: ethyl 4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate(17309-13-6)

Safety Data

• Hazardous Substances Data: 17309-13-6(Hazardous Substances Data)

Usage

General Description

Ethyl 4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate is a chemical compound with the molecular formula C8H9NO2S2. It is a member of the thiazole family, which are heterocyclic organic compounds containing a five-membered ring with sulfur and nitrogen atoms. This particular compound is used in organic synthesis and pharmaceutical research as a building block for more complex molecules. It is also known for its potential antimicrobial and antifungal properties, making it a potential candidate for the development of new drug therapies. However, it is important to handle and use this compound with caution, as it may have hazardous properties and should be handled in accordance with proper safety regulations.

Upstream product

• 89775-91-7 4-hydroxy-4-methyl-2-thioxo-thiazolidine-5-carboxylic acid ethyl ester 
• 513-74-6 ammonium dithiocarbamate 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 75-15-0 carbon disulfide 

Downstream Products

• 13056-63-8 4-methyl-2-(2-oxo-2-phenyl-ethylsulfanyl)-thiazole-5-carboxylic acid ethyl ester 
• 20582-55-2 ethyl 4-methylthiazole-5-carboxylate 
• 1124-01-2 5-(2-hydroxy-ethyl)-4-methyl-3H-thiazole-2-thione 
• 7238-62-2 ethyl 2-chloro-4-methylthiazole-5-carboxylate 
• 40003-43-8 4,4'-dimethyl-2,2'-sulfanediyl-bis-thiazole-5-carboxylic acid diethyl ester 
• 5351-51-9 4,5-dimethyl-3H-thiazole-2-thione 
• 101749-73-9 2-(2-chloro-phenyldisulfanyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 96294-48-3 2-(4-chloro-2-nitro-phenyldisulfanyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 96446-92-3 4-methyl-2-(2-nitro-phenyldisulfanyl)-thiazole-5-carboxylic acid ethyl ester 
• 57658-34-1 4-methyl-2-thioxo-2,3-dihydro-thiazole-5-carboxylic acid 

Relevant articles and documents

HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS

This invention is directed to heteroaryl-substituted sulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy.

Process for Preparing Ethyl-4-methyl-5-thiazolecarboxyate

Provided is a method for preparing ethyl-4-methyl-5-thiazolecarboxylate, used as an intermediate for manufacturing Febuxostat, an arthrifuge, in an efficient and economical manner and environmentally friendly conditions. The method comprises the following steps: (i) reacting ethyl 2-chloroacetoacetate and ammonium dithiocarbamate and obtaining ethyl-4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate; and (ii) desulfurizing ethyl-4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate.COPYRIGHT KIPO 2017

MORPHOLINE COMPOUND

A compound represented by the formula (1) wherein ring A is aryl optionally having substituent(s) and the like; ring B is arylene optionally having substituent(s) and the like; m=0-2; n=1-5; X is a bond and the like; Y is a bond and the like; and Z is hydrogen atom and the like or a pharmaceutically acceptable salt thereof, and a hydrate or solvate thereof have affinity for CCR3, and can be pharmaceutical products for the treatment and/or prophylaxis of immune or inflammatory diseases.