5351-51-9

Basic information

• Product Name: 4,5-DIMETHYL-THIAZOLE-2-THIOL
• Synonyms: 4,5-DIMETHYL-2-MERCAPTOTHIAZOLE;4,5-DIMETHYL-THIAZOLE-2-THIOL;2(3H)-Thiazolethione, 4,5-dimethyl-;4,5-Dimethyl-1,3-thiazole-2-thiol;4-[5-Dimethyl-2-thiazolethiol;4,5-dimethylthiazole-2(3H)-thione;EINECS 226-327-0;4,5-Dimethyl-2(3H)-thiazolethione
• CAS NO: 5351-51-9
• Molecular Formula: C₅H₇NS₂
• Molecular Weight: 145.25
• EINECS: 226-327-0
• Mol File: 5351-51-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 166 °C
• Boiling Point: 215℃
• Flash Point: 84℃
• Appearance: /Solid
• Density: 1.28
• Refractive Index: 1.649
• PKA: 8.68±0.60(Predicted)
• CAS DataBase Reference: 4,5-DIMETHYL-THIAZOLE-2-THIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIMETHYL-THIAZOLE-2-THIOL(5351-51-9)
• EPA Substance Registry System: 4,5-DIMETHYL-THIAZOLE-2-THIOL(5351-51-9)

Safety Data

• Hazardous Substances Data: 5351-51-9(Hazardous Substances Data)

Usage

General Description

4,5-Dimethyl-thiazole-2-thiol is a chemical compound with the formula C5H7NS. It is a thiazole derivative, which is a five-membered ring containing four carbon atoms, one nitrogen atom, and one sulfur atom. 4,5-Dimethyl-thiazole-2-thiol has a strong odor and is often used in the formulation of fragrances and flavorings. It is also used as a chemical intermediate in the synthesis of other organic compounds. Additionally, 4,5-Dimethyl-thiazole-2-thiol has been studied for its potential biological activities, including its antimicrobial and antioxidant properties. Overall, this compound has a variety of industrial and research applications due to its unique chemical structure and properties.

InChI:InChI=1/C28H29N5O4S2/c1-4-32(5-2)39(36,37)25-16-10-12-22(18-25)27-30-31-28(33(27)24-14-7-6-8-15-24)38-19-26(35)29-23-13-9-11-21(17-23)20(3)34/h6-18H,4-5,19H2,1-3H3,(H,29,35)

Upstream product

• 4091-39-8 3-chloro-2-butanone 
• 513-74-6 ammonium dithiocarbamate 
• 814-75-5 3-bromo-butanone 
• 17309-13-6 ethyl 4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate 
• 100135-25-9 2-(4,5-dimethyl-thiazol-2-ylmercapto)-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 64-17-5 ethanol 
• 7783-06-4 hydrogen sulfide 
• 57308-65-3 3-thiocyanobutan-2-one 
• 29947-24-8 2-bromo-4,5-dimethyl-1,3-thiazole 
• 17356-08-0 thiourea 

Downstream Products

• 1402414-75-8 O-benzyl S-4,5-dimethylthiazol-2-yl carbonothioate 
• 91959-25-0 3,4,5-trimethyl-3H-thiazol-2-one benzoylhydrazone 
• 21364-38-5 3,4,5-Trimethyl-Δ⁴-thiazolinthion-(2) 
• 13056-61-6 2-(4,5-dimethyl-thiazol-2-ylsulfanyl)-1-phenyl-ethanone 
• 874509-66-7 4,5-dimethyl-thiazole-2-sulfenic acid amide 
• 3581-91-7 4,5-Dimethylthiazole 
• 95174-23-5 4,5-dimethyl-2-(2-nitro-phenyldisulfanyl)-thiazole 

Relevant articles and documents

CARBACEPHEM β-LACTAM ANTIBIOTICS

Carbacephem -lactam antibiotics having structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar1, Ar2, R1 and R2 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.

Studies on acetylenic compounds. XXV. Ring closure. (5). New synthetic method of heterocyclic compounds from alpha-amino- and alpha-N-substituted amino- acetylenic compounds.

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