173186-92-0

Usage

Uses

Used in Pharmaceutical Industry:
(3-methylpiperidin-4-yl)acetic acid ethyl ester is used as a chemical intermediate for the synthesis of pharmaceutical drugs and potential drug candidates. Its ethyl ester form allows for selective manipulation and functionalization of the molecule, making it a valuable building block in medicinal chemistry.
Used in Organic Synthesis:
(3-methylpiperidin-4-yl)acetic acid ethyl ester is used as a protecting group for the carboxylic acid functionality in organic synthesis. This allows for selective reactions to occur at other sites on the molecule, facilitating the preparation and modification of organic compounds through esterification or other chemical transformations.
Used in Research Laboratories:
(3-methylpiperidin-4-yl)acetic acid ethyl ester is used as a chemical reagent in research laboratories for the preparation and modification of organic compounds. Its versatility as a protecting group and building block makes it an important tool in the development of new chemical entities and the study of organic reactions.

Upstream product

• 181269-69-2 tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate 
• 34737-89-8 1-Benzyl-3-methyl-4-piperidon 
• 107418-97-3 ethyl (2E)-(1-benzyl-3-methylpiperidin-4-ylidene)acetate 

Relevant academic research and scientific papers

AZOLE-SUBSTITUTED PYRIDINE COMPOUND

The present invention provides a compound represented by formula [I'| shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme, wherein the structure represented by formula [III] shown below represents any of the structures represented by formula group [IV] shown below, wherein R1 represents a hydrogen atom, a fluorine atom, methyl, etc.; R2, R3, and R4 each independently represent a hydrogen atom, a fluorine atom, or methyl; W represents a single bond, C1-3alkanediyl, or the formula -O-CH2CH2-; and ring A represents (a) substituted C4-6cycloalkyl, (b) substituted 4- to 6-membered saturated nitrogen-containing heterocyclyl, (c) substituted phenyl, (d) substituted pyridyl, (e) substituted 2,3-dihydrobenzofuran, (f) 4- to 6-membered saturated oxygen-containing heterocyclyl, etc.

Carboxymethyl piperidine derivative

The present invention provides a novel compound useful in the prevention or treatment of nausea and vomiting associated with the administration of antineoplastics, the compound having an NK1 receptor-antagonizing effect, and an inhibitory effect on CYP3A4 that is attenuated to a greater extent than in aprepitant. Specifically, the present invention relates to a carboxymethyl piperidine derivative represented by formula (I) or a pharmacologically acceptable salt thereof. In the formula, ring A is a benzene ring or the like, ring B is a pyridine ring or the like, R1 is a C1-6 alkyl or C1-6 alkoxy, R2 and R3 are hydrogen atoms or methyl, and n represents an integer of from 0 to 5.

CARBOXYMETHYL PIPERIDINE DERIVATIVE

The present invention provides a new compound which has NK1 receptor antagonist activity, whose CYP3A4 inhibitory activity is reduced compared to aprepitant, and which are useful for the prevention or treatment of cancer-chemotherapy-induced nausea and vomiting. That is, the present invention relates to carboxymethyl piperidine derivatives represented by the following formula (I) or a pharmaceutically acceptable salt thereof. Wherein, ring A is a benzene ring or the like; ring B is a pyridine ring or the like; R1 is C1-6 alkyl or C1-6 alkoxy; R2 and R3 are a hydrogen atom or methyl; and n is an integral number from 0 to 5.

N-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl methyl)-piperidine derivatives as antidepressants

The invention relates to substituted nitrogenous heterocycles derivatives of general formula (I) STR1 in the racemic or optically pure form and/or in the form of cis/trans isomers, their pharmaceutically acceptable salts, and their use for preparing drugs