1732-25-8

Upstream product

• 1732-13-4 1,2,3,6,7,8-hexahydropyrene 
• 75-15-0 carbon disulfide 
• 7726-95-6 bromine 
• 129-00-0 pyrene 

Downstream Products

• 1732-26-9 4-bromopyrene 
• 69795-73-9 3-hydroxy-3,4-dihydrocyclopentapyrene 
• 22245-55-2 pyren-4-ylacetic acid 
• 69795-70-6 cyclopentapyrene-3(4H)-one 
• 27208-37-3 cyclopenta[c,d]pyrene 
• 3353-12-6 4-methylpyrene 

Relevant academic research and scientific papers

Comparison Study of the Site-Effect on Regioisomeric Pyridyl-Pyrene Conjugates: Synthesis, Structures, and Photophysical Properties

To investigate the "site effect" of pyridyl substituents on a pyrene core, four regioisomeric monopyridyl-pyrene (1-4) and five regioisomeric dipyridyl-pyrene (5-9) conjugates were synthesized and characterized and their structures confirmed by single-crystal X-ray diffraction. The photophysical properties and related frontier orbital features of these compounds have been studied both experimentally and theoretically and demonstrate the dependence of the properties of the compounds on the position of substitution of the pyridyl moieties connecting to the pyrene core. It was found that the absorption spectra of 2- A nd 4-substituted pyrene derivatives display similar and weak influence on the S2 a? S0 excitations, whereas they are quite different from those of 1-substituted isomers. The emission spectra of 1- A nd 4-substituted pyrenes are quite similar, whereas those of 2-substituted isomers display the largest bathochromic shift. The 1,6-disubstituted compound 5 exhibits a near-unity emission quantum yield in solution, which is nearly three times higher than those of other regioisomeric dipyridyl-pyrenes. In addition, the tetrasubstituted 1,6-dipyridyl-3,8-di-n-butyl-pyrene (10) exhibits the highest solid-state quantum yield of 0.24 among all of the 10 pyridyl-pyrenes prepared in this study.

A novel 4-hydroxypyrene-based “off–on” fluorescent probe with large Stokes shift for detecting cysteine and its application in living cells

This paper reports a novel fluorescent probe 4-acrylatepyrene (PYAC) based on 4-hydroxypyrene, which can effectively detect cysteine (Cys). The probe PYAC uses acrylate moiety as a recognition site and has relatively high selectivity and sensitivity for Cys with the detection limit of 0.062 μM. After treatment with Cys, PYAC exhibits “off–on” switching property and large Stokes shift (171 nm). Due to nucleophilic addition and specific intramolecular cyclization, it exhibits higher selectivity for Cys than other amino acids and common ions, including homocysteine (Hcy) and glutathione (GSH) with similar structures to Cys. The recognition mechanism has been characterized by high-performance liquid chromatography (HPLC) and nuclear magnetic resonance spectroscopy (1H NMR). Anti-interference test and pH influence test display it is suitable for detecting Cys in living cells. Finally, the probe PYAC has been successfully applied to cell imaging with negligible cytotoxicity.

Phenanthroquinazoline-core compounds

Provided is a composition comprising one or more phenanthroquinazoline-core compounds having structure (I)wherein each of R 1 and R 2 is independently a substituted or unsubstituted phenyl group.

Derivatised molecules for mass spectrometry

Compounds of formula (IIa): are provided where:X is a group capable of being cleaved from the α-carbon atom to form an ion of formula (I')C is a carbon atom bearing a single positive charge or a single negative charge; The invention further provides compounds of formula (IIb): where:X is a counter-ion to C. The compounds of formula (IIa) and (IIb) may form ions of formula (I') by either cleaving the C-X bond between X and the α-carbon atoms in the case of the compounds of formula (IIa) or dissociating X in the case of compounds of formula (IIb).

Synthese d'analogues furannique et nitro-2 furannique du benzopyrene

Pyrenofuran, a heterocyclic analogue of benzopyrene, and its 10-nitro derivative were prepared in six steps starting from 5-formyl-4-hydroxypyrene.These isomers of the previously described pyrenofuran, pyrenofuran, 10-nitropyrenofuran and 10-nitropyrenofuran are of particular interest due to their mutagenic activities.