173277-45-7Relevant academic research and scientific papers
Synthetic Routes to 1,5-Dihydro-5-oxo-4,1-benzoxazepines and to 5-Oxooxazoloquinolines
Gandhi, Sham S.,Bell, Karen L.,Gibson, Martin S.
, p. 13301 - 13308 (1995)
The literature concerning phenacyl anthranilate, N-phenacylanthranilic acid and phenacyl N-phenacylanthranilate is clarified.Phenacyl anthranilate is dehydrated to 1,5-dihydro-5-oxo-2-phenyl-4,1-benzoxazepine by treatment with phosphoryl chloride; other examples of this reaction are described.A preparation of 4-methyl-5-oxo-2-phenyloxazoloquinoline from N-phenacylanthranilic acid and propionic anhydride is reported.
SYNTHESIS OF 2-ARYL-3-HYDROXYQUINOLIN-4(1H)-ONES
Hradil, Pavel,Jirman, Josef
, p. 1357 - 1366 (2007/10/02)
Eight substituted phenacyl anthranilates have been prepared by reaction of sodium anthranilate with substituted phenacyl halides in dimethylformamide in the yields from 31 to 93percent.The phenacyl esters were cyclized in polyphosphoric acid or by mere heating to give the respective substituted 2-aryl-3-hydroxyquinolin-4(1H)-ones in the yields from 77 to 98percent.All the compounds prepared have been characterized by their 1H and 13C NMR spectra.
