Synthetic Routes to 1,5-Dihydro-5-oxo-4,1-benzoxazepines and to 5-Oxooxazoloquinolines

DOI: 10.1016/0040-4020(95)00880-H

Source and publish data:

Tetrahedron p. 13301 - 13308 (1995)

Update date:2022-08-04

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Authors:

Gandhi, Sham S.

Bell, Karen L.

Gibson, Martin S.

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Article abstract of DOI:10.1016/0040-4020(95)00880-H

The literature concerning phenacyl anthranilate, N-phenacylanthranilic acid and phenacyl N-phenacylanthranilate is clarified.Phenacyl anthranilate is dehydrated to 1,5-dihydro-5-oxo-2-phenyl-4,1-benzoxazepine by treatment with phosphoryl chloride; other examples of this reaction are described.A preparation of 4-methyl-5-oxo-2-phenyloxazolo<3,2-a>quinoline from N-phenacylanthranilic acid and propionic anhydride is reported.

Full text of DOI:10.1016/0040-4020(95)00880-H

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