1733-62-6

Usage

InChI:InChI=1/C19H14N4O4/c24-22(25)16-11-12-17(18(13-16)23(26)27)20-21-19(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-13,20H

Upstream product

• 64-17-5 ethanol 
• 29586-02-5 N²-nitroso-1,1,N²-triphenyl-methanon hydrazone 
• 76368-93-9 benzophenone (2-nitrophenyl)hydrazone 
• 2675-31-2 benzophenone-(4-nitro-phenylhydrazone) 
• 102478-11-5 2,2-diphenylvinyl 4-methylbenzenesulfonate 
• 71-43-2 benzene 
• 110-46-3 isopentyl nitrite 
• 60-29-7 diethyl ether 
• 10544-72-6 dinitrogen tetraoxide 
• 574-61-8 benzophenone N-phenylhydrazone 
• 2712-78-9 bis-[(trifluoroacetoxy)iodo]benzene 
• 31382-54-4 1,1,4-triphenylpenta-1,3-diene 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 91-01-0 1,1-Diphenylmethanol 

Downstream Products

• 119-61-9 benzophenone 
• 360-11-2 difluorodiphenylmethane 
• 615-71-4 benzene-1,2,4-triamine 

Relevant academic research and scientific papers

Hydrogen Bonding in Phenylhydrazone Derivatives of Benzophenone: Crystal and Molecular Structures of Benzophenone (2-Nitrophenyl)hydrazone, containing an Intramolecular NO2...NH...? Bifurcated Hydrogen Bond, and Benzophenone (4-Nitrophenyl)hydrazone, cont

Crystal structures have been determined of the two title compounds.The (2-nitrophenyl)hydrazone (2) is monoclinic, space group P21/a, Z = 4, with a = 12.074(5), b = 12.771(8), c = 11.998(8) Angstroem, β = 118.0 deg.The (4-nitrophenyl)hydrazone

Synthesis and Antimicrobial Resistant Modulatory Activity of 2,4-Dinitrophenylhydrazone Derivatives as Agents against Some ESKAPE Human Pathogens

A library of six novel phenylhydrazones were synthesized and evaluated for their in vitro antimicrobial and resistance modulating activity against a panel of Gram-positive, Gram-negative, and fungal species. The compounds were produced in good yields of 6

Oxidation of benzhydrol by tetrabutylammoniumbromochromate in presence and absence of picolinic acid and 1,10-phenanthroline: A kinetic study

The oxidation of benzhydrol (BH) by tetrabutylammoniumbromochromate (TBABC) was studied in aqueous acetic acid medium. The reaction is first order with respect to tetrabutylammoniumbromochromate, benzhydrol and [H+] and the reaction is catalyzed by hydrogen ions. The reaction has been studied in the presence of picolinic acid and 1,10-phenanthroline as promoters. The promoters used in this oxidation reaction, picolinic acid and 1,10-phenanthroline are strong chelating ligands which form complexes with most transition metal ions. Among the two promoters oxidation is much faster with 1,10-phenanthroline. The low dielectric constant of the medium assists the complex formation and enhances the reactivity. The reactions were studied at different temperatures at different acetic acid-water composition and various thermodynamic parameters have been determined. The observed experimental results have been explained by plausible mechanisms.

Kinetics and mechanism of oxidation of aliphatic secondary alcohols by benzyltrimethylammonium chlorobromate

Oxidation of several secondary alcohols by benzyltrimethylammonium chlorobromate (BTMACB) in aqueous acetic acid leads to the formation of corresponding ketones. The reaction is first order with respect to BTMACB and the alcohols. The reaction failed to induce the polymerization of acrylonitrile. There is no effect of tetrabutylammonium chloride on the reaction rate. The proposed reactive oxidizing species is chlorobromate ion. The oxidation of benzhydrol-α-d (PhCDOHPh) exhibited a substantial primary kinetic isotope effect (kH/kD = 5.61 at 298 K). The effect of solvent composition indicated that the rate increases with an increase in the polarity of the solvent. The reaction is susceptible to both the polar and steric effects of the substituents. A mechanism involving transfer of a hydride ion in the ratedetermining step has been proposed.

Oxidative cleavage and rearrangement of aryl epoxides using iodosylbenzene: On criegee's trail

Aryl epoxides undergo rearrangement and oxidative cleavage when reacted with in situ prepared hydroxy-λ3-iodane complexes. The presence of H2O plays a decisive role in steering the reaction path. A mechanistic scheme is proposed that accounts for the observed chemoselectivities. Copyright

Specific features of the reaction of vanadyl acetylacetonate with tert-butyl hydroperoxide

Reaction of vanadyl acetylacetonate with tert-butyl hydroperoxide (benzene, 20°C) at any molar ratio leads to the elimination of ligand and its oxidation mainly to CO2 and acetic acid. At the (acac)2VO: t-BuOOH ratio above 1:10 liberation of oxygen partially in the singlet state takes place.

Diazodiphenylmethane and monosubstituted butadienes: Kinetics and a new chapter of vinylcyclopropane chemistry

Diazodiphenylmethane (DDM) undergoes cycloadditions to 1-substituted buta-1,3-dienes exclusively at the C(3)=C(4) bond. At room temperature, the N2 loss from the initially formed 4,5-dihydro-3H-pyrazoles 2 is faster than the cycloaddition and furnishes the vinylcyclopropane derivatives 7 and 9 with structural retention at the C(1)=C(2) bond. 2-Substituted butadienes react with DDM at the C(3)=C(4) bond to give 12; isoprene, however, affords 3,4/1,2 products in the ratio of 86:14. DDM is a nucleophilic 1,3-dipole: 1-Cyanobutadiene reacts 400 times faster than 1-methoxybuta-1,3-diene (DMF, 40°). The log k2 for the additions to six 1-substituted butadienes show a linear correlation with σp (Hammett) and ρ = +2.9; the log k2 of five 2-substituted butadienes are linearly related to Taft's σI (ρ = +1.7). The structures of the vinylcyclopropanes 7, 9, and 12 are established by NMR spectra and oxidation. A cyclopropyl carbinyl cation is made responsible for the isomerization of 12, R = Ph, Me, by acetic acid to 4-substituted 1,1-diphenylpenta-1,3-dienes 25 and 29; TsOH at 200° converts 25 further to 9,10-dihydro-9-methyl-10-phenyl-9,10-ethanoanthracene (27). Thermal rearrangement of 7, 9, and 12 at 200-300° produces the 3- or 1-substituted 4,4-diphenylcyclopentenes 30 and 31. These give the same mass spectra as the vinylcyclopropanes, and an open-chain distonic radical cation is suggested as common intermediate. Besides spectroscopic evidence for the cyclopentene structures, hydrogenation and epoxidation are described; NMR data support the trans-attack by perbenzoic acid.

CONJUGATED AROMATIC COMPOUNDS FOR DIAGNOSIS AND THERAPY

Disclosed herein are compounds, compositions and methods for using such compounds and compositions in the treatment of hyperproliferative conditions, including precancerous and cancerous conditions. In one embodiment, the compounds include resonance modul

Ferric(III) nitrate supported on kieselguhr: A new reagent for selective oxidation of alcohols

A selective and effective oxidation of alcohols into the corresponding aldehydes and ketones, respectively, with a new reagent, ferric(III) nitrate supported on kieselguhr, under heterogeneous conditions is reported. Copyright Taylor & Francis Group, LLC.