2675-31-2Relevant articles and documents
Synthesis of 1: H -indazoles by an electrochemical radical Csp2-H/N-H cyclization of arylhydrazones
Alhumade, Hesham,Lei, Aiwen,Li, Dongting,Wan, Hao,Xia, Huadan,Yang, Liwen,Yi, Hong
supporting information, p. 665 - 668 (2022/01/22)
The development of efficient and sustainable C-N bond-forming reactions to N-heterocyclic frameworks has been a long-standing interest in organic synthesis. In this work, we develop an electrochemical radical Csp2-H/N-H cyclization of arylhydrazones to 1H-indazoles. The electrochemical anodic oxidation approach was adopted to synthesize a variety of 1H-indazole derivatives in moderate to good yields. HFIP was not only employed as a solvent or the proton donor, but also can promote the formation of N free radicals. This synthetic methodology is operationally simple, and less expensive electrodes would be suitable for this chemistry. This journal is
Divergent Synthesis of 1H-Indazoles and 1H-Pyrazoles from Hydrazones via Iodine-Mediated Intramolecular Aryl and sp3 C–H Amination
Wei, Wei,Wang, Zhen,Yang, Xikang,Yu, Wenquan,Chang, Junbiao
, p. 3378 - 3387 (2017/10/09)
A divergent intramolecular C–H amination of hydrazones has been developed employing molecular iodine (I2) as the sole oxidant. The required hydrazone substrates were readily obtained by condensation of hydrazines with the corresponding ketones.
Hydrogen Bonding in Phenylhydrazone Derivatives of Benzophenone: Crystal and Molecular Structures of Benzophenone (2-Nitrophenyl)hydrazone, containing an Intramolecular NO2...NH...? Bifurcated Hydrogen Bond, and Benzophenone (4-Nitrophenyl)hydrazone, cont
Drew, Michael G. B.,Willey, Gerald R.
, p. 215 - 220 (2007/10/02)
Crystal structures have been determined of the two title compounds.The (2-nitrophenyl)hydrazone (2) is monoclinic, space group P21/a, Z = 4, with a = 12.074(5), b = 12.771(8), c = 11.998(8) Angstroem, β = 118.0 deg.The (4-nitrophenyl)hydrazone