173336-76-0

Basic information

• Product Name: 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene
• Synonyms: 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene;Benzene, 4-bromo-1-methoxy-2-(3-methoxypropoxy)-;EOS-61552
• CAS NO: 173336-76-0
• Molecular Formula: C₁₁H₁₅BrO₃
• Molecular Weight: 275.139
• EINECS: 1312995-182-4
• Product Categories: aliskiren
• Mol File: 173336-76-0.mol
• Article Data: 16

Chemical Properties

• Melting Point: 39℃
• Boiling Point: 309℃
• Flash Point: 124℃
• Appearance: /
• Density: 1.313
• Vapor Pressure: 0.00121mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene(173336-76-0)
• EPA Substance Registry System: 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene(173336-76-0)

Safety Data

• Hazardous Substances Data: 173336-76-0(Hazardous Substances Data)

Usage

General Description

4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene, also known as 4-bromo-1-methoxy-2-(3-methoxypropoxy)benzene, is a chemical compound with the molecular formula C11H15BrO3. It is a benzene derivative with a bromo and methoxy group attached to the carbon ring, as well as a 3-methoxypropoxy side chain. 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds due to its unique chemical structure. 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene is also known for its potential as a building block in the design and development of new drugs and bioactive molecules. Additionally, it may have applications in the field of organic chemistry and materials science.

InChI:InChI=1/C11H15BrO3/c1-13-6-3-7-15-11-8-9(12)4-5-10(11)14-2/h4-5,8H,3,6-7H2,1-2H3

Upstream product

• 36865-41-5 3-bromopropanol methyl ether 
• 37942-01-1 5-bromo-2-methoxyphenol 
• 36215-07-3 1-Chloro-3-methoxypropane 

Downstream Products

• 934841-22-2 C₃₀H₄₇NO₈ 
• 1024754-25-3 3-[4-methoxy-3-(3-methoxypropoxy)phenyl]prop-2-yn-1-ol 
• 1257529-92-2 (3S,5S)-5-((1S,3S)-1-Azido-3-(hydroxy(4-methoxy-3-(3-methoxypropoxy)phenyl)methyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one 
• 935847-26-0 (2S,7S,E)-2,7-diisopropyloct-4-enedioic acid 
• 1200341-29-2 (1R,2S)-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)pent-4-en-1-ol 
• 878276-60-9 carbonic acid 2-tert-butoxycarbonylamino-4-[4-methoxy-3-(3-methoxypropoxy)benzoyl]-5-methylhexyl ester tert-butyl ester 
• 173334-57-1 (2S,4S,5S,7S)-5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonanoic acid (2-carbamoyl-2-methyl-propyl)-amide 
• 173338-07-3 tert-butyl (3S,5S,6S,8S)-8-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-6-hydroxy-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-2,9-dimethyldecan-5-ylcarbamate 
• 866030-35-5 tert-butyl {(1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}carbamate 
• 1236549-00-0 {(1S,3S)-1-((2S,4S)-4-isopropyl-5-oxo-furanidin-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid benzyl ester 
• 1236549-06-6 (1S,2S,4S)-4-(2-carbamoyl-2-methylpropyl-carbamoyl)-2-hydroxy-1-{(S)-2-[4-methoxy-3-(3-methoxypropoxy)-benzyl]-3-methylbutyl}-5-methylhexyl-carbamic acid benzyl ester 
• 1290075-65-8 C₃₂H₄₅NO₆ 
• 1027526-91-5 C₃₂H₄₅NO₇ 
• 1309922-65-3 (3S,5R)-5-((1R,3S)-1-Hydroxy-3-(4-methoxy-3-(methoxypropoxy)benzoyl)-4-methylpentyl)-3-isopropyl-dihydrofuran-2(3H)-one 

Relevant articles and documents

Development of DHQ-based chemical biology probe to profile cellular targets for HBV

Chronic hepatitis B virus (HBV) infection has been a serious public health burden worldwide. Current anti-HBV therapies could not eliminate HBV ultimately. Considering the characteristics of HBV, it is impossible to be entirely cured based on current therapies. Therefore, it is urgently needed to develop novel therapeutic agents with new mechanism of action. The dihydroquinolizinone (DHQ) derivatives exhibited potent anti-HBV activity by decreasing HBV DNA and HBsAg level in an obscure mechanism of action. In this study, we have optimized the DHQ scaffold, developed the photoaffinity probe, with which to identify potential binding proteins.

NOVEL OXA-AND AZA-TRICYCLIC 4-PYRIDONE-3-CARBOXYLIC ACID FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

Provided herein are oxa- and aza-tricyclic 4-pyridone-3-carboxylic acid compounds, their manufacture, pharmaceutical compositions comprising them, and their use as medicaments for inhibiting HBsAg secretion and HBV DNA production, and for treatment and/or prophylaxis of hepatitis B infection.

Novel isoquinoline compound and medical application thereof

The invention relates to an isoquinoline compound shown as a formula (A) or a stereoisomer, a pharmaceutically acceptable salt, a hydrate, a solvate or a crystal thereof, a medicinal composition thereof and application thereof as antiviral medicines. The isoquinoline compound inhibits hepatitis B DNA activity and hepatitis B surface antigen activity at the same time. The invention particularly relates to application thereof to preparation of medicines for treating and/or preventing hepatitis B, hepatitis B viruses (HBV) thereof and other viral infectious diseases, in particular to treatment and/or prevention of the hepatitis B and the hepatitis B viruses as HBV Surface antigen inhibitor medicines and HBV DNA production inhibitor medicines.