36215-07-3Relevant articles and documents
Synthesis, structural study, and in vitro trypanocidal and antitumour activities of tetrakis(3-methoxypropyl)tin and (3-methoxypropyl)tin chlorides
Lebl, Tomas,Smicka, Ales,Brus, Jiri,Bruhn, Clemens
, p. 143 - 148 (2003)
A set of four water-soluble (3-methoxypropyl)stannanes of general formula (CH3OCH2CH2CH2)x SnCl4-x, where x = 4 (1), x = 3 (2), x = 2 (3), and x = 1 (4), was prepared. For 3 and 4, which were isolated in the crystalline state, it was shown by X-ray diffraction that the tin atom is coordinated in distorted octahedral and trigonal-bipyramidal geometries, respectively (i.e., the oxygen atoms of the 3-methoxypropyl groups were coordinated to the central tin atom in both cases, forming chelates). For all compounds, structures in CDCl3 and [D6]DMSO solutions were proposed on the basis of their 13C and 119Sn NMR spectra. In CDCl3 solution, the degree of donor-acceptor bonding between the central tin atom and oxygen atom of the 3-methoxypropyl substituent was evaluated on the basis of 17O NMR chemical shifts and 3,6J(1H, 119Sn) long-range coupling constants. Compounds 2 and 3 exhibited promising in vitro antitumour and trypanocidal activities. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2003.
Asymmetric organocatalytic electrophilic phosphination
Nielsen, Martin,Jacobsen, Christian Borch,Jorgensen, Karl Anker
supporting information; experimental part, p. 3211 - 3214 (2011/05/17)
Meeting the challenge: The first asymmetric catalytic C*-P bond formation employing electrophilic phosphorus compounds has been developed using a catalytic amount of a dimeric cinchona alkaloid, and a subsequent one-pot process to deliver high stereoselectivities and good yields of α-quaternary α-phosphino β-amino acids (see scheme). 31P-NMR experiments suggest a novel reaction mechanism wherein a cinchona alkaloid nucleophilically activates the phosphorus electrophile. Copyright
INTERMEDIATE COMPOUND OF TECHNETIUM NITRIDE COMPLEX FOR RADIODIAGNOSTIC IMAGING
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Page/Page column 6, (2010/07/04)
A bisphosphonoaminc compound represented by the following formula (I): wherein R1, R2, R3, R4 and R5 are independently an alkyl group having 1 to 6 carbon atoms, and n is an integer of 1 to 6, is extremely useful as an intermediate for preparing a technetium nitride complex for radiodiagnostic imaging.
