17336-47-9

Basic information

• Product Name: AURORA 763
• Synonyms: AURORA 763;N'-[(E)-(3-nitrophenyl)methylidene]pyridine-3-carbohydrazide
• CAS NO: 17336-47-9
• Molecular Formula: C₁₃H₁₀N₄O₃
• Molecular Weight: 270.24
• Mol File: 17336-47-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: AURORA 763(CAS DataBase Reference)
• NIST Chemistry Reference: AURORA 763(17336-47-9)
• EPA Substance Registry System: AURORA 763(17336-47-9)

Safety Data

• Hazardous Substances Data: 17336-47-9(Hazardous Substances Data)

Upstream product

• 553-53-7 Nicotinic acid hydrazide 
• 99-61-6 3-nitro-benzaldehyde 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 614-18-6 3-pyridinecarboxylic acid ethyl ester 
• 59-67-6 nicotinic acid 

Downstream Products

• 89813-93-4 1-(2-(3-nitro-phenyl)-5-pyridin-3-yl-(1,3,4)oxadiazol-3-yl)ethanone 
• 1345545-66-5 N-(2-(3-nitrophenyl)-4-oxothiazolidin-3-yl)nicotinamide 

Relevant articles and documents

Design, synthesis and molecular docking studies of new azomethine derivatives as promising anti-inflammatory agents

Herein, we synthesized a series of Ibuprofen-based 4a-k, quinoxaline-based 9a-f and pyridine-based 13a-h azomethine derivatives and studied their anti-inflammatory potency. The in-silico docking studies of the synthesized compounds 4a-k revealed better af

Antimicrobial activities of synthetic arylidine nicotinic and isonicotinic hydrazones

Background: Despite availability of variety of antibacterial agents, re-emergance of pathogenic bacteria is still a serious medical concern. Identification of new, safer, and selective antibacterial agents is the key interest in the medicinal chemistry research. Methods: A library of synthetic arylidene nicotinic and isonicotinic hydrazones (1-63) were investigated for antimicrobial activities. Results: A number of derivatives showed significant to moderate antimicrobial activities against Gram positive and Gram negative bacterial cultures. Few compounds also showed antifungal activity against fungal cultures. Minimum Inhibitory Concentration (MIC) was calculated for the most active compounds 1, 7, 11, 19, 34, 46, 50, 51, and 55 against gram positive and gram negative cultures. Conclusion: Newly identified compounds may serve as lead for future research in order to get the more powerful antibacterial agents.

Metal-Free Synthesis of 1,3,4-Oxadiazoles from N′-(Arylmethyl)hydrazides or 1-(Arylmethyl)-2-(arylmethylene)hydrazines

An efficient and versatile metal-free synthesis of 1,3,4-oxadiazoles from N′-(arylmethyl)hydrazides or 1-(arylmethyl)-2-(arylmethylene)hydrazines through oxidative dehydrogenation is reported. A range of 2,5-disubstituted 1,3,4-oxadiazoles were prepared by treating N′-(arylmethyl)hydrazides with (diacetoxyiodo)benzene in acetonitrile or by treating 1-(arylmethyl)-2-(arylmethylene)hydrazines with [bis(trifluoroacetoxy)iodo]benzene in methyl tert-butyl ether. Aldehyde N-acylhydrazones and aldazines were initially generated in situ as intermediates.