17336-90-2

Basic information

• Product Name: 3,4-Dimethyl-2(1H)-quinolinone
• Synonyms: 3,4-Dimethyl-2(1H)-quinolinone;3,4-Dimethylcarbostyril
• CAS NO: 17336-90-2
• Molecular Formula: C11H11NO
• Molecular Weight: 0
• Mol File: 17336-90-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 348.7°C at 760 mmHg
• Flash Point: 205.1°C
• Appearance: /
• Density: 1.095g/cm³
• Vapor Pressure: 4.96E-05mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 3,4-Dimethyl-2(1H)-quinolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dimethyl-2(1H)-quinolinone(17336-90-2)
• EPA Substance Registry System: 3,4-Dimethyl-2(1H)-quinolinone(17336-90-2)

Safety Data

• Hazardous Substances Data: 17336-90-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 2242, 1956 DOI: 10.1021/ja01591a059

InChI:InChI=1/C11H11NO/c1-7-8(2)11(13)12-10-6-4-3-5-9(7)10/h3-6H,1-2H3,(H,12,13)

Upstream product

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• 124-38-9 carbon dioxide 
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• 88426-94-2 3-methyl-2-hydroxytryptophol 
• 62-53-3 aniline 
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Relevant articles and documents

Lactamization of alkenyl C-H bonds to generate 2-quinolinones with triphosgene

A simple and easy-going method is developed to synthesize the analogues of 2-quinolinones by using triphosgene (BTC) as the carbonyl source. In these reactions, both the toxic carbon monoxide (CO) and phosgene are avoided and the 2-quinolinones are obtained in moderate to good yields under mild conditions, all of which are anticipated to be meaningful in both industry and laboratory.

The formation of quinolin-2(1H)-ones via electrocyclic reaction of o-isocyanatostyrenes generated in situ from o-isocyanostyrenes

A convenient one-pot preparation of 4-substituted or 3,4-disubstituted quinolin-2(1H)-ones from 2-isocyanostyrene derivatives, which involves mCPBA oxidation to the corresponding isocyanate intermediates followed by electrocyclization, is described.

Reactions of 2-Hydroxytryptophol: Results of Strong Acid and Alkaline Treatments of 2-Hydroxytryptophol

Upon being warmed at 90 deg C in trifluoromethanesulfonic acid for 42-78 h, 2-hydroxytriptophol (4a) gave 3-ethylideneoxidoles (E- and Z-form) (5a), while 3-methyl- (4b) or 3-ethyl-2-hydroxytryptophol (4c) gave the corresponding 3-alkylideneoxindoles (5b,