173377-13-4

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 63584-42-9 (Z)-1-ethylthio-1-(trimethylsiloxy)propene 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 478011-20-0 (E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester 
• 478011-19-7 (+)-E-2,E-6-(4R,5S)-3,5-dimethoxy-4-methyl-7-phenyl-hepta-2,6-dienoic acid methyl ester 
• 910131-53-2 (+)-E-(2R,3S)-5-methoxy-4-methyl-3-oxo-7-phenyl-hept-6-enoic acid methyl ester 
• 478011-21-1 (E)-(4S,5S)-3-Hydroxy-5-methoxy-4-methyl-7-phenyl-hept-6-enoic acid methyl ester 
• 138694-19-6 (2R,3R,4E)-3-Methoxy-2-methyl-5-phenyl-4-pentenal 

Relevant academic research and scientific papers

The first synthesis and antifungal activities of 9-methoxystrobilurin-type β-substituted β-Methoxyacrylate

The first synthesis of 9-methoxystrobilurin-type β-substituted MOAs was successfully achieved. A chiral oudemansin-type β-substituted MOA was also synthesized utilizing Mukaiyama's asymmetric aldol reaction. Antifungal activities of the synthesized compounds against several representative fungi were examined by disk-diffusion assay. As a result, unique and superior antifungal properties of 9-methoxystrobilurin-type β-substituted MOAs compared with those of oudemansin-type analogue were clearly revealed.

Highly Stereoselective Synthesis of Both Enantiomers of 2-Methyl-3-Hydroxythioesters by Asymmetric Aldol Reactions Using Similar Types of Chiral Sources Derived from L-Proline

Both enantiomers of 2-methyl-3-hydroxythioesters have been synthesized in chiral tin(II) Lewis acid-mediated aldol reactions of silyl enolate 3 with aldehydes, by simply choosing similar types of chiral sources, 4 and 5, derived from L-proline.