910131-53-2

Upstream product

• 88644-06-8 (+)-E-(2R,3S)-3-methoxy-2-methyl-5-phenyl-pent-4-enoic acid 
• 79-20-9 acetic acid methyl ester 
• 478011-20-0 (E)-(2R,3S)-3-Methoxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester 
• 910131-70-3 (-)-(4R,5S)-3-(E-(2R,3S)-3-methoxy-2-methyl-5-phenyl-pent-4-enoyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 14371-10-9 (E)-3-phenylpropenal 
• 478011-21-1 (E)-(4S,5S)-3-Hydroxy-5-methoxy-4-methyl-7-phenyl-hept-6-enoic acid methyl ester 
• 173377-13-4 (E)-(2R,3S)-3-Hydroxy-2-methyl-5-phenyl-pent-4-enethioic acid S-ethyl ester 
• 138694-19-6 (2R,3R,4E)-3-Methoxy-2-methyl-5-phenyl-4-pentenal 
• 138694-16-3 (4R,5S)-3-<(2R,3R,4E)-3-Hydroxy-2-methyl-5-phenyl-4-pentenoyl>-4-methyl-5-phenyl-2-oxazolidinone 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 478011-19-7 (+)-E-2,E-6-(4R,5S)-3,5-dimethoxy-4-methyl-7-phenyl-hepta-2,6-dienoic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of myxothiazols, novel bis-thiazole β-methoxyacrylate- based anti-fungal compounds from myxobacteria

Convergent total syntheses of myxothiazols A and Z are described. The syntheses are based on elaboration of the (S)-E,E-diene thioamide 22, conversion of 22 into the bis-thiazole 27 and Wittig reactions between 27c and the aldehyde 30. The substituted β-m

The first synthesis and antifungal activities of 9-methoxystrobilurin-type β-substituted β-Methoxyacrylate

The first synthesis of 9-methoxystrobilurin-type β-substituted MOAs was successfully achieved. A chiral oudemansin-type β-substituted MOA was also synthesized utilizing Mukaiyama's asymmetric aldol reaction. Antifungal activities of the synthesized compounds against several representative fungi were examined by disk-diffusion assay. As a result, unique and superior antifungal properties of 9-methoxystrobilurin-type β-substituted MOAs compared with those of oudemansin-type analogue were clearly revealed.