17345-66-3

Basic information

• Product Name: 2,3,4-TRIHYDROXYDIPHENYLMETHANE
• Synonyms: 2,3,4-TRIHYDROXYDIPHENYLMETHANE;4-BENZYLPYROGALLOL;1,2,3-Benzenetriol, 4-(phenylmethyl)-
• CAS NO: 17345-66-3
• Molecular Formula: C₁₃H₁₂O₃
• Molecular Weight: 216.23
• Product Categories: Color Former & Related Compounds;Developer;Functional Materials
• Mol File: 17345-66-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 94.0 to 98.0 °C
• Boiling Point: 255 °C / 12mmHg
• Flash Point: 114.825°C
• Appearance: /
• Density: 1.254g/cm³
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.396
• Solubility: soluble in Methanol
• PKA: 9.70±0.15(Predicted)
• CAS DataBase Reference: 2,3,4-TRIHYDROXYDIPHENYLMETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-TRIHYDROXYDIPHENYLMETHANE(17345-66-3)
• EPA Substance Registry System: 2,3,4-TRIHYDROXYDIPHENYLMETHANE(17345-66-3)

Safety Data

• Hazardous Substances Data: 17345-66-3(Hazardous Substances Data)

Usage

General Description

2,3,4-Trihydroxydiphenylmethane is a chemical compound with the molecular formula C13H10O4. It is a triphenylmethane dye and a derivative of diphenylmethane. 2,3,4-TRIHYDROXYDIPHENYLMETHANE is commonly used in the production of dyes and pigments. It has three hydroxyl groups, which make it highly reactive and useful in various chemical reactions. 2,3,4-Trihydroxydiphenylmethane is also known for its antioxidant properties and is used in some pharmaceutical and cosmetic applications. Overall, this compound plays an important role in the chemical industry and has various practical applications.

InChI:InChI=1/C9H11F3O4/c1-3-16-8(15)6(4-5(2)13)7(14)9(10,11)12/h6H,3-4H2,1-2H3

Upstream product

• 100-44-7 benzyl chloride 
• 87-66-1 2-hydroxyresorcinol 
• 1143-72-2 2,3,4-trihydroxybenzophenone 

Downstream Products

• 1472655-89-2 6-benzyl-7,8-dihydroxy-4-(trifluoromethyl)-2H-chromen-2-one 

Relevant articles and documents

New convenient approach for the synthesis of benzyl 2H-chromenones and their α-amylase inhibitory, ABTS+ scavenging activities

Series of new benzyl 2H-chromenones 6a-n was synthesized by Pechmann condensation of substituted benzyl resorcinols 2a-c and 3a with various β-ketoesters such as ethyl 3-oxobutanoate, ethyl 3-oxo-3-phenylpropanoate, ethyl 4-chloro-3-oxobutanoate, ethyl 4,4,4-trifluoro-3-oxobutanoate and ethyl 2-chloro-3-oxobutanoate 5a-e in very good yields. Synthesized compounds 6a-n were screened for their α-amylase inhibitory, and ABTS+ scavenging activities. In the present series of compounds, compound 8-benzyl-7-hydroxy-4-phenyl-2H-chromen-2-one 6c and 8-benzyl-7-hydroxy-4-methyl- 2H-chromen-2-one 6a were most potent ABTS+ radical scavenging and α-amylase inhibitor. Although compound 6,8-dibenzyl-7-hydroxy-4- (trifluoromethyl)-2H-chromen-2-one 6h displayed potent ABTS+ free radical scavenging potential, it was found poor in inhibiting pancreatic α-amylase.