17377-97-8

Basic information

• Product Name: FURAN-2-YLMETHYL-(4-METHOXY-PHENYL)-AMINE
• Synonyms: TIMTEC-BB SBB011053;FURAN-2-YLMETHYL-(4-METHOXY-PHENYL)-AMINE;N-(FURAN-2-YLMETHYL)-4-METHOXYANILINE
• CAS NO: 17377-97-8
• Molecular Formula: C₁₂H₁₃NO₂
• Molecular Weight: 203.24
• Mol File: 17377-97-8.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 324.2°Cat760mmHg
• Flash Point: 149.9°C
• Appearance: /
• Density: 1.152g/cm³
• Vapor Pressure: 2.82E-15mmHg at 25°C
• CAS DataBase Reference: FURAN-2-YLMETHYL-(4-METHOXY-PHENYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: FURAN-2-YLMETHYL-(4-METHOXY-PHENYL)-AMINE(17377-97-8)
• EPA Substance Registry System: FURAN-2-YLMETHYL-(4-METHOXY-PHENYL)-AMINE(17377-97-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 17377-97-8(Hazardous Substances Data)

Usage

General Description

Furan-2-ylmethyl-(4-methoxy-phenyl)-amine is a chemical compound that combines a furan ring, a methoxyphenyl group and an amine group. The furan ring is a five-sided, heterocyclic organic compound that includes an oxygen atom. The methoxyphenyl portion of the compound indicates the presence of a methoxy group (-OCH3) attached to a phenyl ring – a component of the compound benzene, which is a basic unit in organic chemistry. Finally, the amine group is a functional group that contains a basic nitrogen atom with a lone pair, often appearing in organic chemistry. FURAN-2-YLMETHYL-(4-METHOXY-PHENYL)-AMINE is very specific and may be used in niche areas of chemical research and development. Information about its exact uses and properties may not be readily available and may require further research.

InChI:InChI=1/C13H13N3.C8H6O4/c14-13(15)16(11-7-3-1-4-8-11)12-9-5-2-6-10-12;9-7(10)5-3-1-2-4-6(5)8(11)12/h1-10H,(H3,14,15);1-4H,(H,9,10)(H,11,12)

Upstream product

• 1749-14-0 N-furfurylidene-p-anisidine 
• 10257-32-6 D-ribose 
• 87-72-9 L-(+)-arabinose 
• 2460-44-8 β-D-xylopyranoside 
• 617-89-0 furan-2-ylmethanamine 
• 19820-47-4 4-methoxyphenyl 2,2-dimethylpropionate 
• 98-01-1 furfural 
• 623-12-1 4-chloromethoxybenzene 
• 98-00-0 (2-furyl)methyl alcohol 
• 104-94-9 4-methoxy-aniline 
• 100239-11-0 (E)-N-2-furylidene-4-methoxyaniline 

Downstream Products

• 17960-79-1 2-(4-methoxy-phenyl)-1,2,3,6,7,7a-hexahydro-3a,6-epioxido-isoindole 
• 114142-96-0 6-[Furan-2-ylmethyl-(4-methoxy-phenyl)-amino]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbaldehyde 
• 17960-71-3 N-allyl-N-furfuryl-4-methoxy-aniline 
• 1749-14-0 N-furfurylidene-p-anisidine 
• 100239-11-0 (E)-N-2-furylidene-4-methoxyaniline 
• 1507344-49-1 C₁₃H₁₂N₂O₂ 
• 114143-13-4 11-(4-Methoxy-phenyl)-1,3-dimethyl-10,11-dihydro-1H,6aH-6,9-dioxa-1,3,5,11-tetraaza-pentaleno[1,6a-a]naphthalene-2,4-dione 
• 114143-02-1 6-[Furan-2-ylmethyl-(4-methoxy-phenyl)-amino]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbaldehyde oxime 

Relevant articles and documents

PAd2-DalPhos Enables the Nickel-Catalyzed C?N Cross-Coupling of Primary Heteroarylamines and (Hetero)aryl Chlorides

Base-metal catalysts capable of enabling the assembly of heteroatom-dense molecules by cross-coupling of primary heteroarylamines and (hetero)aryl chlorides, while sought-after given the ubiquity of unsymmetrical di(hetero)arylamino fragments in pharmacophores, are unknown. Herein, we disclose the new “double cage” bisphosphine PAd2-DalPhos (L2). The derived air-stable NiII pre-catalyst C2 functions well at low loadings in challenging test C?N cross-couplings with established substrates, and facilitates the first Ni-catalyzed C?N cross-couplings of primary five- or six-membered ring heteroarylamines and activated (hetero)aryl chlorides, with synthetically useful scope that is competitive with Pd catalysis.

Direct Reductive Amination of Aldehydes Using Hantzsch Ester Promoted by N,N′-Diphenyl-S-Benzylisothiouronium Iodide as an Organocatalyst

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Improving C=N bond reductions with (Cyclopentadienone)iron complexes: Scope and limitations

Herein, we broaden the application scope of (cyclo-pentadienone)iron complexes 1 in C=N bond reduction. The catalytic scope of pre-catalyst 1b, which is more active than the “Kn?lker complex” (1a) and other members of its family, has been expanded to the catalytic transfer hydrogenation (CTH) of a wider range of aldimines and ketimines, either pre-isolated or generated in situ. The kinetics of 1b-promoted CTH of ketimine S1 were assessed, showing a pseudo-first order profile, with TOF = 6.07 h–1 at 50 % conversion. Moreover, the chiral complex 1c and its analog 1d were employed in the enantioselective reduction of ketimines and reductive amination of ketones, giving fair to good yields and moderate enantioselectivity.