173781-70-9

Basic information

• Product Name: BENZOYL CHLORIDE,4-(2-PHENYLETHYL)-
• Synonyms: BENZOYL CHLORIDE,4-(2-PHENYLETHYL)-
• CAS NO: 173781-70-9
• Molecular Formula: C₁₅H₁₃ClO
• Molecular Weight: 0
• Mol File: 173781-70-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BENZOYL CHLORIDE,4-(2-PHENYLETHYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZOYL CHLORIDE,4-(2-PHENYLETHYL)-(173781-70-9)
• EPA Substance Registry System: BENZOYL CHLORIDE,4-(2-PHENYLETHYL)-(173781-70-9)

Safety Data

• Hazardous Substances Data: 173781-70-9(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 1253-46-9 4-methoxycarbonylbenzyltriphenylphosphonium bromide 
• 14518-67-3 methyl 4-(phenylethyl)benzoate 
• 1149-18-4 (E)-methyl 4-styrylbenzoate 
• 785-79-5 4-phenethylbenzoic acid 

Relevant articles and documents

4-Aminoquinolines: Novel nociceptin antagonists with analgesic activity

Small-molecule nociceptin antagonists were synthesized to examine their therapeutic potential. After a 4-aminoquinoline derivative was found to bind with the human ORL1 receptor, a series of 4-aminoquinolines and related compounds were synthesized and their binding was evaluated. Elucidation of structure - Activity relationships eventually led to the optimum compounds. One of these compounds, N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide hydrochloride (11) not only antagonized nociceptin-induced allodynia in mice but also showed analgesic effect in a hot plate test using mice and in a formalin test using rats. Its analgesic effect was not antagonized by the opioid antagonist naloxone. These results indicate that this nociceptin antagonist has the potential to become a novel type of analgesic that differs from μ-opioid agonists.