17380-77-7 Usage
General Description
1-Phenylcyclobutylamine, also known as PCBA, is a chemical compound that belongs to the class of amines. It is a cyclic amine that contains a phenyl group attached to a four-membered cyclobutyl ring. PCBA has been studied for its potential pharmacological properties, including its potential as a central nervous system stimulant and as a potential precursor for the synthesis of other psychoactive substances. It has also been investigated for its potential use in the treatment of depression and anxiety disorders. Additionally, PCBA has been evaluated for its potential as a drug discovery tool in the development of new therapeutic agents. However, further research and evaluation are needed to fully understand the potential effects and applications of PCBA.
Check Digit Verification of cas no
The CAS Registry Mumber 17380-77-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,8 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17380-77:
(7*1)+(6*7)+(5*3)+(4*8)+(3*0)+(2*7)+(1*7)=117
117 % 10 = 7
So 17380-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H13N/c11-10(7-4-8-10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8,11H2
17380-77-7Relevant articles and documents
A Hofmann Rearrangement-Ring Expansion Cascade for the Synthesis of 1-Pyrrolines: Application to the Synthesis of 2,3-Dihydro-1H-pyrrolo[2,1-a]isoquinolinium Salts
Huang, He,Yang, Qinghua,Zhang, Qianqian,Wu, Jie,Liu, Yizhen,Song, Chuanjun,Chang, Junbiao
, p. 1130 - 1135 (2016/04/19)
Treatment of cyclobutanecarboxamide with bis(trifluoroacetoxy)iodobenzene, PhI(OCOCF3)2, resulted in the formation of 1-pyrroline via Hofmann rearrangement of the former followed by in situ ring expansion reaction of the cyclobutylamine intermediate. Further elaboration of this methodology to the synthesis of 2,3-dihydro-1H-pyrrolo[2,1-a]isoquinolinium salts has also been described.
