17388-70-4 Usage
Uses
Used in Pharmaceutical Research and Development:
Z-TRP-GLY-OH is used as a research compound for exploring the biological activities and potential therapeutic applications of L-tryptophan and glycine. Z-TRP-GLY-OH's unique structure and the presence of the Z group may enhance its stability and bioavailability, allowing for more effective targeting of specific biological pathways.
Used in Mood Regulation and Sleep Disorders:
Z-TRP-GLY-OH is used as a precursor for serotonin synthesis, which plays a crucial role in mood regulation and sleep. Z-TRP-GLY-OH may be employed in the development of pharmaceuticals aimed at treating mood disorders and sleep disturbances by modulating serotonin levels in the brain.
Used in Protein Synthesis and Enzyme Function:
As a compound containing both essential and nonessential amino acids, Z-TRP-GLY-OH is used in the study of protein synthesis and enzyme function. Z-TRP-GLY-OH may be utilized in research to understand the role of L-tryptophan and glycine in the synthesis of proteins and enzymes, as well as their impact on various biological processes.
Used in Neurotransmitter Research:
Z-TRP-GLY-OH is used as a research tool to study the role of neurotransmitters, particularly serotonin, in the central nervous system. Z-TRP-GLY-OH may be employed in the development of drugs targeting neurotransmitter pathways to treat neurological and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 17388-70-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,8 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17388-70:
(7*1)+(6*7)+(5*3)+(4*8)+(3*8)+(2*7)+(1*0)=134
134 % 10 = 4
So 17388-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H21N3O5/c25-19(26)12-23-20(27)18(10-15-11-22-17-9-5-4-8-16(15)17)24-21(28)29-13-14-6-2-1-3-7-14/h1-9,11,18,22H,10,12-13H2,(H,23,27)(H,24,28)(H,25,26)
17388-70-4Relevant articles and documents
Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles
Celik, Ilhami,Abdel-Fattah, Ashraf A.A.
experimental part, p. 4923 - 4929 (2009/10/09)
N-Protected dipeptidoylbenzotriazoles react with aqueous ammonia to give dipeptide primary amides (77-98%) and with N-unprotected α-amino amides to afford tripeptide primary amides (82-86%).
Synthesis of Ethylamide of Cyclic Undecapeptide Corresponding to the 593 - 603 Sequence of Transmembrane Glycoprotein gp41 of Human Immunodeficiency Virus Type Two
Sidorova, M. V.,Kudryavtseva, E. V.,Molokoedov, A. S.,Ovchinnikov, M. V.,Bespalova, Zh. D.
, p. 582 - 589 (2007/10/03)
Ethylamide of cyclic disulfide of the HIV-2 peptide antigen corresponding to the 593 - 603 sequence of the gp41 protein was synthesized by conventional methods of peptide chemistry in solution.The absence of racemization during fragment condensation was s
SYNTHESIS AND EVALUATION OF ANTIGENIC PROPERTIES OF PEPTIDES OF THE HIV-1 PROTEIN GP 41
Bespalova, Zhanna D.,Pekelis, Boris L.,Deigin, Vladislav I.,Yarova, Elena P.,Saks, Tatyana P.,et al.
, p. 2537 - 2554 (2007/10/02)
Scheme is described for the synthesis of 19- and 21-member peptides which constitute a part of the domain (sequence 584-609) from the conservative region of the transmembrane protein gp 41 HIV-1.The synthesis was carried out using standard methods of pept
Synthesis and some pharmacological properties of [8-L-tryptophan]oxytocin.
Bodanszky,Tolle,Seto,Sawyer
, p. 1259 - 1261 (2007/10/02)
Condensation of (tert-butyloxycarbonyl)tocinoic acid with L-prolyl-L-tryptophylglycinamide produced the Boc derivative of a nonapeptide (disulfide) which on deprotection afforded [8-L-tryptophan]oxytocin. In assays on the rat uterus in vitro and in vivo t
