17388-70-4 Usage
Description
Z-TRP-GLY-OH is a chemical compound composed of the amino acids L-tryptophan (TRP) and glycine (GLY), with a Z group at the N-terminus and a carboxylic acid group at the C-terminus. L-tryptophan is an essential amino acid involved in protein synthesis, serotonin production, and mood and sleep regulation, while glycine is a nonessential amino acid important for the synthesis of proteins, enzymes, and other molecules in the body. Z-TRP-GLY-OH may have potential applications in pharmaceutical research and development due to the biological activities of its constituent amino acids and their ability to influence various biological pathways.
Uses
Used in Pharmaceutical Research and Development:
Z-TRP-GLY-OH is used as a research compound for exploring the biological activities and potential therapeutic applications of L-tryptophan and glycine. Z-TRP-GLY-OH's unique structure and the presence of the Z group may enhance its stability and bioavailability, allowing for more effective targeting of specific biological pathways.
Used in Mood Regulation and Sleep Disorders:
Z-TRP-GLY-OH is used as a precursor for serotonin synthesis, which plays a crucial role in mood regulation and sleep. Z-TRP-GLY-OH may be employed in the development of pharmaceuticals aimed at treating mood disorders and sleep disturbances by modulating serotonin levels in the brain.
Used in Protein Synthesis and Enzyme Function:
As a compound containing both essential and nonessential amino acids, Z-TRP-GLY-OH is used in the study of protein synthesis and enzyme function. Z-TRP-GLY-OH may be utilized in research to understand the role of L-tryptophan and glycine in the synthesis of proteins and enzymes, as well as their impact on various biological processes.
Used in Neurotransmitter Research:
Z-TRP-GLY-OH is used as a research tool to study the role of neurotransmitters, particularly serotonin, in the central nervous system. Z-TRP-GLY-OH may be employed in the development of drugs targeting neurotransmitter pathways to treat neurological and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 17388-70-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,8 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17388-70:
(7*1)+(6*7)+(5*3)+(4*8)+(3*8)+(2*7)+(1*0)=134
134 % 10 = 4
So 17388-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H21N3O5/c25-19(26)12-23-20(27)18(10-15-11-22-17-9-5-4-8-16(15)17)24-21(28)29-13-14-6-2-1-3-7-14/h1-9,11,18,22H,10,12-13H2,(H,23,27)(H,24,28)(H,25,26)
17388-70-4Relevant articles and documents
Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles
Celik, Ilhami,Abdel-Fattah, Ashraf A.A.
experimental part, p. 4923 - 4929 (2009/10/09)
N-Protected dipeptidoylbenzotriazoles react with aqueous ammonia to give dipeptide primary amides (77-98%) and with N-unprotected α-amino amides to afford tripeptide primary amides (82-86%).
SYNTHESIS AND EVALUATION OF ANTIGENIC PROPERTIES OF PEPTIDES OF THE HIV-1 PROTEIN GP 41
Bespalova, Zhanna D.,Pekelis, Boris L.,Deigin, Vladislav I.,Yarova, Elena P.,Saks, Tatyana P.,et al.
, p. 2537 - 2554 (2007/10/02)
Scheme is described for the synthesis of 19- and 21-member peptides which constitute a part of the domain (sequence 584-609) from the conservative region of the transmembrane protein gp 41 HIV-1.The synthesis was carried out using standard methods of pept
