173901-09-2

Basic information

• Product Name: [(R)-2-(6-Chloro-pyridin-3-yl)-2-hydroxy-ethyl]-[2-(4-nitro-phenyl)-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [(R)-2-(6-Chloro-pyridin-3-yl)-2-hydroxy-ethyl]-[2-(4-nitro-phenyl)-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 173901-09-2
• Molecular Weight: 421.881
• Mol File: 173901-09-2.mol

Chemical Properties

• CAS DataBase Reference: [(R)-2-(6-Chloro-pyridin-3-yl)-2-hydroxy-ethyl]-[2-(4-nitro-phenyl)-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(R)-2-(6-Chloro-pyridin-3-yl)-2-hydroxy-ethyl]-[2-(4-nitro-phenyl)-ethyl]-carbamic acid tert-butyl ester(173901-09-2)
• EPA Substance Registry System: [(R)-2-(6-Chloro-pyridin-3-yl)-2-hydroxy-ethyl]-[2-(4-nitro-phenyl)-ethyl]-carbamic acid tert-butyl ester(173901-09-2)

Safety Data

• Hazardous Substances Data: 173901-09-2(Hazardous Substances Data)

Upstream product

• 173901-07-0 (R)-α-Bromomethyl-3-(6-chloropyridine)methanol 
• 173901-08-1 2-chloro-5-[(2R)-oxiran-2-yl]pyridine 
• 55676-22-7 3-acetyl-6-chloropyridine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 

Downstream Products

• 173901-20-7 (2-{4-[4-(3-Hexyl-ureido)-benzenesulfonylamino]-phenyl}-ethyl)-((R)-2-hydroxy-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

3-pyridylethanolamines: Potent and selective human β3 adrenergic receptor agonists

The 3-pyridylethanolamine L-757,793 is a potent β3 AR agonist (EC50 6.3 nM, 70% activation) with 1,300- and 500-fold selectivity over binding to the β1 and β2 ARs, respectively. L-757,793 stimulated lipolysis in rhesus monkeys (ED50 0.2 mg/kg) with a maximum response equivalent to that elicited by isoproterenol.