55676-22-7

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-acetylpyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its reactivity and ability to form complex molecular structures. It plays a crucial role in the development of new drugs and the improvement of existing ones, contributing to advancements in medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-5-acetylpyridine is employed as a building block for the creation of novel agrochemicals. Its unique properties allow for the development of more effective and targeted pesticides, herbicides, and other agricultural chemicals, enhancing crop protection and yield.

Upstream product

• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 
• 58757-38-3 6-Chloronicotinoyl chloride 
• 75-16-1 methylmagnesium bromide 
• 4684-94-0 6-chloropicolinic acid 
• 33252-28-7 6-chloronicotinonitrile 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 431-03-8 dimethylglyoxal 
• 149281-42-5 6-chloro-N-methoxy-N-methylpyridine-3-carboxamide 
• 53939-30-3 5-bromo-2-chloropyridine 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 216317-64-5 ethyl 3-(6-chloropyridin-3-yl)-3-oxopropanoate 
• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 
• 108-59-8 malonic acid dimethyl ester 
• 67-68-5 dimethyl sulfoxide 

Downstream Products

• 265107-43-5 1-(6-morpholin-4-yl-pyridin-3-yl)-ethanone 
• 23092-75-3 1-(6-chloropyridin-3-yl)ethanol 
• 265107-41-3 1-[6-(dimethylamino)-3-pyridinyl]ethanone 
• 214697-26-4 4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidine 
• 856014-52-3 2-amino-4-(3-bromophenyl)-6-(2-dimethylamino-5-pyridyl)nicotinonitrile 
• 867256-56-2 4-(5-acetyl-pyridin-2-yl)-benzoic acid methyl ester 
• 257609-07-7 6-(4-benzyloxyphenoxy)-3-acetylpyridine 
• 1194091-72-9 C₁₄H₁₃NO₂ 
• 1211536-35-4 1-(6-ethylpyridin-3-yl)-ethanone 

Relevant academic research and scientific papers

Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions

A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.

Method for removing acyl group in diazo of aryl diazonium salt

The invention provides a method for removing an acyl group in diazo of an aryl diazonium salt. The method is characterized in that the aryl diazonium salt and its derivative and an ortho-dicarbonyl compound undergo an illumination reaction to obtain a corresponding arylacyl product. The method has the advantages of high yield of the product, no metal involvement, and simple process.

INHIBITORS OF MUTANT ISOCITRATE DEHYDROGENASES AND COMPOSITIONS AND METHODS THEREOF

The invention provides novel chemical compounds useful for treating cancer, or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.

pyrrole logical sequence handkerchief nai intermediate preparation method (by machine translation)

The invention relates to a simple operation, raw materials are easy, and the production cost is low, the quality of the product is good and is suitable for the industrial production of the intermediate pyrrole logical sequence handkerchief nai 5 - (pyridine - 2 - yl) - 2 (1H) - pyridone of the preparation method. (by machine translation)

High-activity iminophenylacetate compound, preparation method and applications thereof

The present invention belongs to the field of pesticides, and particularly relates to a high-activity iminophenylacetate compound, a preparation method and applications thereof. According to the present invention, the research of novel methoxy acrylate compounds is performed, a pyridine aryl ether structure is introduced into the structure of the novel methoxy acrylate compound, the research of the new compound structures is expanded, and the high-activity iminophenylacetate compound is found; and the compound has the bioactivity equal to azoxystrobin and trifloxystrobin, provides good effects on most pathogenic bacteria, especially provides significant prevention and treatment effects on Sclerotinia sclerotiorum bacterial, and is effective at a low doses.

New Positive allosteric modulators of nicotinic acetylcholine receptor

The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine α7 receptor.

PRODUCTION PROCESS OF 2,3'-BIPYRIDYL-6'-ONE

A production process where 2,3′-bipyridyl-6′-one can be produced in high purity at low cost on an industrial scale without using an expensive catalyst or special equipment is provided. A process for producing 2,3′-bipyridyl-6′-one comprises reacting an acetylpyridine derivative with at least one of compounds represented by formulae (II) to (V) to synthesize a bipyridine derivative and hydrolyzing the bipyridine derivative by one-pot preparation. In formulae (II) to (V), each of R2 to R8, X and Y represents a given group.

Synthesis of a neonicotinoide pesticide derivative via chemoenzymatic dynamic kinetic resolution

(Chemical Equation Presented) Chemoenzymatic dynamic kinetic resolution (DKR) via combined ruthenium and enzyme catalysis was used in the key step of a synthesis of a neonicotinoid pesticide derivative (S)-3. The DKR was carried out under mild conditions

PROCESS FOR PRODUCTION OF 2,3'-BIPYRIDYL-6'-ONE

A production process where 2,3'-bipyridyl-6'-one can be produced in high purity at low cost on an industrial scale without using an expensive catalyst or special equipment is provided. A process for producing 2,3'-bipyridyl-6'-one comprises reacting an acetylpyridine derivative with at least one of compounds represented by formulae (II) to (V) to synthesize a bipyridine derivative and hydrolyzing the bipyridine derivative by one-pot preparation. In formulae (II) to (V), each of R2 to R8, X and Y represents a given group.

NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS

This invention relates to novel sulfonamide substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.