55676-22-7

Basic information

• Product Name: 2-Chloro-5-acetylpyridine
• Synonyms: 1-(6-CHLORO-3-PYRIDINYL)-1-ETHANONE;1-(6-CHLOROPYRIDIN-3-YL)ETHANONE;2-CHLORO-5-ACETYLPYRIDINE;6-CHLORO-3-ACETYLPYRIDINE;1-(6-CHLOROPYRIDIN-3-YL)ETHANONE ,97%;1-(6-Chloropyridin-3-yl)ethan-1-one;5-Acetyl-2-chloropyridine;3-Acetyl-6-chloropyridine
• CAS NO: 55676-22-7
• Molecular Formula: C₇H₆ClNO
• Molecular Weight: 155.58
• Product Categories: Heterocycle-Pyridine series
• Mol File: 55676-22-7.mol
• Article Data: 35

Chemical Properties

• Melting Point: 98 °C
• Boiling Point: 280.46 °C at 760 mmHg
• Flash Point: 123.418 °C
• Appearance: /
• Density: 1.233 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -2.14±0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-5-acetylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-acetylpyridine(55676-22-7)
• EPA Substance Registry System: 2-Chloro-5-acetylpyridine(55676-22-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 55676-22-7(Hazardous Substances Data)

Usage

General Description

2-Chloro-5-acetylpyridine, also known as 5-Acetyl-2-chloropyridine, is a chemical compound with the molecular formula C7H6ClNO. It is a chlorinated derivative of pyridine, an aromatic heterocyclic compound. 2-Chloro-5-acetylpyridine is a clear, colorless liquid with a sweet, fruity odor. It is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Due to its reactivity and potential health hazards, it is important to handle 2-Chloro-5-acetylpyridine with proper safety precautions in a controlled laboratory environment.

Upstream product

• 33252-28-7 6-chloronicotinonitrile 
• 917-64-6 methyl magnesium iodide 
• 60-29-7 diethyl ether 
• 58757-38-3 6-Chloronicotinoyl chloride 
• 108-59-8 malonic acid dimethyl ester 
• 75-16-1 methylmagnesium bromide 
• 149281-42-5 6-chloro-N-methoxy-N-methylpyridine-3-carboxamide 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 431-03-8 dimethylglyoxal 
• 53939-30-3 5-bromo-2-chloropyridine 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 216317-64-5 ethyl 3-(6-chloropyridin-3-yl)-3-oxopropanoate 
• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 
• 4684-94-0 6-chloropicolinic acid 

Downstream Products

• 23794-13-0 2-chloro-5-(2-bromoacetyl)pyridine 
• 257609-07-7 6-(4-benzyloxyphenoxy)-3-acetylpyridine 
• 1211536-35-4 1-(6-ethylpyridin-3-yl)-ethanone 
• 173901-20-7 (2-{4-[4-(3-Hexyl-ureido)-benzenesulfonylamino]-phenyl}-ethyl)-((R)-2-hydroxy-2-pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions

A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.

INHIBITORS OF MUTANT ISOCITRATE DEHYDROGENASES AND COMPOSITIONS AND METHODS THEREOF

The invention provides novel chemical compounds useful for treating cancer, or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.

pyrrole logical sequence handkerchief nai intermediate preparation method (by machine translation)

The invention relates to a simple operation, raw materials are easy, and the production cost is low, the quality of the product is good and is suitable for the industrial production of the intermediate pyrrole logical sequence handkerchief nai 5 - (pyridine - 2 - yl) - 2 (1H) - pyridone of the preparation method. (by machine translation)