173913-74-1

Basic information

• Product Name: 5-(benzenesulfonyloxy)-2-methylpyridine
• Synonyms: 5-(benzenesulfonyloxy)-2-methylpyridine
• CAS NO: 173913-74-1
• Molecular Weight: 249.29
• Mol File: 173913-74-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-(benzenesulfonyloxy)-2-methylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzenesulfonyloxy)-2-methylpyridine(173913-74-1)
• EPA Substance Registry System: 5-(benzenesulfonyloxy)-2-methylpyridine(173913-74-1)

Safety Data

• Hazardous Substances Data: 173913-74-1(Hazardous Substances Data)

Upstream product

• 1121-78-4 5-Hydroxy-2-methylpyridine 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 663604-00-0 5-benzenesulfonyloxy-2-methylpyridine N-oxide 
• 173913-77-4 <-2S>-N-(2-hydroxy-1-methyl-2-phenylethyl)-N-methyl 2-amino-3-(2-(5-benzenesulfonyloxy)pyridyl)propionamide 
• 173913-76-3 5-(benzenesulfonyloxy)-2-(iodomethyl)pyridine 
• 663604-02-2 5-benzenesulfonyloxy-2-hydroxymethylpyridyldiphenylphosphate 
• 663604-03-3 (2R,5S)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-[(5-benzenesulfonyloxypyridin-2-yl)methyl]pyrazine 
• 663604-04-4 methyl (2S)-2-amino-3-(5-benzenesulfonyloxypyridin-2-yl)propanoate 
• 663604-01-1 5-benzenesulfonyloxy-2-hydroxymethylpyridine 
• 185389-91-7 (2R)-2-amino-3-(5-hydroxypyridin-2-yl)propanoic acid 
• 58525-82-9 L-azatyrosine 
• 925443-80-7 2-piperidin-1-ylmethyl-5-{3-[4-(1-trityl-1H-imidazol-4-ylmethyl)-piperidin-1-yl]-propoxy}-pyridine 
• 925443-56-7 benzenesulfonic acid 6-piperidin-1-ylmethyl-pyridin-3-yl ester 
• 173913-75-2 5-(benzenesulfonyloxy)-2-(bromomethyl)pyridine 

Relevant articles and documents

Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl] piperidine series of histamine H3 receptor antagonists

A novel series of histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine template displaying low CYP2D6 and CYP3A4 inhibitory profiles has been identified. Structural features responsible for the reduction of P450 activity, a typical liability of 4-substituted imidazoles, have been established.

Synthesis of l-azatyrosine using pseudoephedrine as a chiral auxiliary

A practical synthesis of the potential chemotherapeutic agent L-azatyrosine is described. The key step involved the alkylation of (R,R)-(-)-pseudoephedrine glycinamide with 5-benzenesulfonyloxy-2-iodomethylpyridine and proceeded in 70-95% yield and 89-95%