58525-82-9Relevant academic research and scientific papers
Efficient large-scale synthesis of Boc-L-azatyrosine
Germain, Herve,Harris, Craig S.,Renaud, Fabrice,Warin, Nicolas
experimental part, p. 523 - 530 (2009/06/20)
A rapid and convenient process for the synthesis of Boc-L-azatyrosine is described from commercially available Boc-β-iodo-Ala-OMe. Copyright Taylor & Francis Group, LLC.
A stereocontrolled synthesis of (R)- and (S)-azatyrosine
Cremonesi, Giuseppe,Dalla Croce, Piero,La Rosa, Concetta,Pizzatti, Enrica
, p. 563 - 567 (2007/10/03)
An asymmetric synthesis of (R)- or (S)- azatyrosine, starting from (2S)- or (2R)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazine (5) (Scho?llkopf reagent) and 5-benzenesulfonyloxy-2-hydroxymethylpyridine (3), is reported. The diastereocontrolled addition gi
Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine.
Adamczyk,Akireddy,Reddy
, p. 3157 - 3159 (2007/10/03)
[reaction: see text] A novel method for the synthesis of (2-pyridyl)alanines 2a-b was developed by converting (2-pyridyl)dehydroamino acid derivatives 1a-b to the corresponding N-oxides 3a-b followed by asymmetric hydrogenation using (R,R)-[Rh(Et-DUPHOS)(
Enzymatic synthesis of aza-L-tyrosines
Watkins,Phillips, Robert S.
, p. 2099 - 2100 (2007/10/03)
Tyrosine phenol-lyase from Citrobacter freundii synthesizes 2-aza-L-tyrosine and 3-aza-L-tyrosine from 3-hydroxypyridine and 2-hydroxypyridine, respectively, and ammonium pyruvate.
A concise synthesis of either enantiomer of azatyrosine
Cooper, Margaret S.,Seton, Alison W.,Stevens, Malcolm F. G.,Westwell, Andrew D.
, p. 2613 - 2616 (2007/10/03)
A facile route to either enantiomer of azatyrosine is reported, utilising an efficient enzymic resolution of protected azatyrosine ethyl ester by α-chymotrypsin as a key step.
