1740-25-6

Basic information

• Product Name: 1H-Imidazole, 2-(2-bromophenyl)-4,5-diphenyl-
• CAS NO: 1740-25-6
• Molecular Formula: C21H15BrN2
• Molecular Weight: 375.267
• Mol File: 1740-25-6.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 2-(2-bromophenyl)-4,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 2-(2-bromophenyl)-4,5-diphenyl-(1740-25-6)
• EPA Substance Registry System: 1H-Imidazole, 2-(2-bromophenyl)-4,5-diphenyl-(1740-25-6)

Safety Data

• Hazardous Substances Data: 1740-25-6(Hazardous Substances Data)

Usage

Class of compound

Imidazole

Structure

Five-membered aromatic ring with two nitrogen atoms and three carbon atoms

Substituents

2-(2-bromophenyl) and 4,5-diphenyl

Reactivity

Versatile

Therapeutic properties

Potential antifungal and antibacterial properties

Applications

Organic synthesis, pharmaceutical research, and drug development.

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 6630-33-7 ortho-bromobenzaldehyde 
• 134-81-6 benzil 

Downstream Products

• 484-47-9 lophine 
• 52747-80-5 2,3-diphenylimidazo[1,2-c]quinazoline 
• 94863-15-7 2-(4,5-diphenyl-1H-imidazol-2-yl)phenylamine 

Relevant articles and documents

Copper-Catalyzed Synthesis of Dibenzo[ b, f ]imidazo[1,2- d ][1,4]oxazepine Derivatives via a Double Ullmann Coupling Reaction

A double Ullmann coupling reaction successfully takes place between 4,5-diaryl-2-(2-bromophenyl)-1 H -imidazoles and 2-bromophenols in the presence of Cs 2 CO 3. This procedure is catalyzed by copper(I) iodide and o -phenanthroline a

Construction of trinuclear N-fused hybrid scaffolds by coupling and cyclization of 2-bromoaryl- and 2-bromovinylimidazoles with ureas under recyclable Cu/C–Al2O3 catalysis

2-(2-Bromoaryl)- and 2-(2-bromovinyl)imidazoles are coupled and cyclized with cyclic ureas as building blocks under recyclable heterogeneous Cu/C–Al2O3 catalysis to afford a class of trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]imidazo[1,2-c]quinazolines and benzo[4,5]imidazo[1,2-a]imidazo[1,2-c]pyrimidines, respectively. The Cu/C–Al2O3 catalytic system could be recovered and reused three times without any loss of catalytic activity.

Facile synthesis of imidazoles by an efficient and eco-friendly heterogeneous catalytic system constructed of Fe3O4 and Cu2O nanoparticles, and guarana as a natural basis

In this study, an efficient hybrid nanocatalyst made of guar gum (guarana, as a natural basis), magnetic iron oxide nanoparticles, and copper(I) oxide nanoparticles (Cu2O NPs) is fabricated and suitably applied for catalyzing the multicomponent (three- and four-component) synthesis reactions of imidazole derivatives. Here, an easy preparation strategy for this novel catalytic system (Cu2O/Fe3O4@guarana) is presented. Then, the application of this catalytic system for the synthesis of imidazole derivatives is precisely investigated. For this purpose, ultrasonication is introduced as an efficient and fast method. In summary, the high catalytic efficiency of Cu2O/Fe3O4@guarana nanocomposite is well demonstrated by high reaction yields obtained in the presence of a small amount of this nanocomposite, under mild conditions. Wide active surface area, substantial magnetic behavior, excellent heterogeneity, suitable stability, well reusability, and etc. have distinguished this catalytic system as an instrumental tool for facilitating the complex synthetic reactions.