94863-15-7Relevant academic research and scientific papers
Synthesis of Quinazolinones, Imidazo[1,2-c]quinazolines and Imidazo[4,5-c]quinolines through Tandem Reductive Amination of Aryl Halides and Oxidative Amination of C(sp3)–H Bonds
Nandwana, Nitesh Kumar,Dhiman, Shiv,Saini, Hitesh Kumar,Kumar, Indresh,Kumar, Anil
, p. 514 - 522 (2017/02/05)
A tandem multicomponent approach has been described for the synthesis of quinazolinones, imidazo[1,2-c]quinazolines and imidazo[4,5-c]quinolines. The reaction involves a copper-catalyzed reductive amination through azidation followed by reduction and oxidative amination of C(sp3)–H bonds of N,N-dimethylacetamide in the presence of TBHP (tert-butylhydroperoxide) as oxidant. The method uses the easily available sodium azide as a nitrogen source and DMA (N,N-dimethylacetamide) as a one-carbon source for the synthesis of these N-fused heterocycles in good to excellent yields. The reaction can also be used for gram-scale synthesis.
Efficient three-step synthesis of benzo[e]imidazo[1,2-c][1,2,3]triazines
Pilali, Hedieh,Kamazani, Shirin Faraji,Moradi, Shahram,Moghimi, Setareh,Mahdavi, Mohammad,Firoozpour, Loghman,Shafiee, Abbas,Foroumadi, Alireza
supporting information, p. 563 - 567 (2016/05/02)
A novel three-step sequence toward benzo[e]imidazo[1,2-c][1,2,3]triazine derivatives is investigated. This pathway started from commercially available starting materials afforded 5a-h in good to excellent yields. In this method, we took the advantage of d
Highly active and stereospecific polymerization of 1,3-butadiene catalyzed by bis{[2-(4,5-diphenylimidazolyl)phenylimino]phenolate}cobalt(II) complexes
Lv, Shuai,Jie, Suyun,Li, Bo-Geng
, p. 108 - 114 (2015/10/12)
A series of bis{[2-(4,5-diphenylimidazolyl)phenylimino]phenolate}cobalt(II) complexes (C1-C4) has been synthesized and characterized. Single-crystal X-ray analysis demonstrated that the cobalt center was coordinated by two [NNO-] ligands and ad
Synthesis of a novel structural variant of imidazoquinazoline with three-point diversity
Sharma, Sunil,Saha, Biswajit,Sawant, Devesh,Kundu, Bijoy
, p. 1841 - 1847 (2007/10/03)
An efficient strategy for the preparation of a novel structural variant of imidazoquinazolines with three-point diversity has been described. The compounds were obtained by treating benzil with o-nitrobenzaldehyde to give imidazoles, followed by reduction
Imidazo[1,2-c]quinazolines with lipid peroxidation inhibitory effect
Domany, Gyoergy,Gizur, Tibor,Gere, Aniko,Takacs-Novak, Krisztina,Farsang, Gyoergy,Ferenczy, Gyoergy G.,Tarkanyi, Gabor,Demeter, Maria
, p. 181 - 187 (2007/10/03)
A series of imidazo[1,2-c]quinazolines of different lipophilic character was prepared. According to their antioxidant (cyclic voltammetry) properties they all should be potent inhibitors of lipid peroxidation. Under the given circumstances (NADPH-induced lipid peroxidation in rat brain microsomes and Fe2+-induced lipid peroxidation in rat brain homogenate), however, their lipid peroxidation inhibitory activity was strongly dependent on their lipophilicity.
