1740-57-4

Basic information

• Product Name: ISOPHTHALAMIDE
• Synonyms: m-carbamoylbenzamide;ISOPHTHALAMIDE;isophthaldiamide;1,3-Benzenedicarbocamide;1,3-BENZENEDICARBOXAMIDE/ISOPHTHALAMIDE;m-Phthalamide;benzene-1,3-dicarboxamide;1,3-Benzenedicarboxamide
• CAS NO: 1740-57-4
• Molecular Formula: C₈H₈N₂O₂
• Molecular Weight: 164.16
• EINECS: 217-104-9
• Mol File: 1740-57-4.mol
• Article Data: 29

Chemical Properties

• Melting Point: 268-270°C
• Boiling Point: 291.62°C (rough estimate)
• Flash Point: 214.4 °C
• Appearance: /
• Density: 1.2739 (rough estimate)
• Vapor Pressure: 1.26E-07mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• PKA: 15.25±0.50(Predicted)
• BRN: 2045544
• CAS DataBase Reference: ISOPHTHALAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ISOPHTHALAMIDE(1740-57-4)
• EPA Substance Registry System: ISOPHTHALAMIDE(1740-57-4)

Safety Data

• Safety Statements: 22-24/25
• RTECS: CZ2201000
• HazardClass: IRRITANT
• Hazardous Substances Data: 1740-57-4(Hazardous Substances Data)

Usage

General Description

ISOPHTHALAMIDE, also known as 1,3-benzenedicarboxamide, is a chemical compound with the molecular formula C10H10N2O2. It is a white crystalline solid that is primarily used as an intermediate in the production of various polymers, including nylon 6,6 and aramid fibers. Isophthalamide is also used as a curing agent for epoxy resins and as a component in the manufacture of pharmaceuticals and agrochemicals. It has a variety of other industrial applications, including as a lubricant additive, a corrosion inhibitor, and a flame retardant. Isophthalamide is considered to be low in toxicity, but proper handling and safety measures should be observed when working with this chemical.

InChI:InChI=1/C8H8N2O2/c9-7(11)5-2-1-3-6(4-5)8(10)12/h1-4H,(H2,9,11)(H2,10,12)

Upstream product

• 99-63-8 benzene-1,3-dicarbonyl dichloride 
• 1477-55-0 1,3-di(aminomethyl)benzene 
• 626-17-5 benzene-1,3-dicarbonitrile 
• 3441-01-8 3-cyanobenzamide 
• 626-18-6 1,3-dimethanol benzene 
• 626-19-7 Isophthalaldehyde 
• 636-53-3 diethyl isophthalate 
• 36438-66-1 1,3-bis(ethyl carboximidate)bezene dihydrochloride 
• 121-91-5 isophthalic acid 

Downstream Products

• 108-45-2 m-phenylenediamine 
• 288078-72-8 C₃₀H₃₄N₆O₅ 
• 117883-49-5 N,N'-bis-dichlorophosphoryl-isophthalodiimidoyl chloride 
• 258505-26-9 1,3-bis[2-(4-carbethoxy)thiazolyl]benzene 
• 258505-28-1 1,3-bis[2-(4-hydroxymethyl)thiazolyl]benzene 
• 626-17-5 benzene-1,3-dicarbonitrile 
• 121-91-5 isophthalic acid 
• 15458-84-1 Isophthaloyldiisocyanat 
• 17384-48-4 Isophthalsaeure-bis-(aethoxycarbonylamid) 
• 117886-78-9 N,N'-bis-trichlorophosphoranylidene-isophthalamide 
• 3441-01-8 3-cyanobenzamide 

Relevant articles and documents

Extended structures controlled by intramolecular and intermolecular hydrogen bonding: A case study with pyridine-2,6-dicarboxamide, 1,3-benzenedicarboxamide and N,N'-dimethyl-2,6-pyridinedicarboxamide

The small organic molecule pyridine-2,6-dicarboxamide, although known in the literature for some time, exhibits interesting and previously unexplored intermolecular and intramolecular hydrogen bonding both in solid state and in solution. With the aid of X-ray crystallography and variable-temperature NMR spectroscopy, we here demonstrate the presence of a very strong hydrogen bonding network for this molecule both in condensed state and solution. Furthermore, a novel extended hydrogen bonding graph-set has been derived for this molecule in crystalline state. Comparison of pyridine-2,6-dicarboxamide with 1,3-benzenedicarboxamide, where the intramolecular hydrogen bonding to the pyridine ring in the former has been removed, yields a different intermolecular hydrogen bonded structure in the solid state. A new graph-set has been determined for the extended structure of 1,3-benzenedicarboxamide in the solid state. In solution, 1,3-benzenedicarboxamide is shown to maintain a hydrogen bonding pattern that is weaker than that observed with pyridine-2,6-dicarboxamide. Replacement of one hydrogen on each carboxamide nitrogen of pyridine-2,6-dicarboxamide by a methyl group also alters the extended structure to a significant extent. In N,N'-dimethyl-2,6-pyridinedicarboxamide, the three-dimensional hydrogen bonding pattern observed with pyridine-2,6-dicarboxamide all but collapses to one-dimensional chains. (C) 2000 Elsevier Science B.V.

Preparation method of M-phenylenediamine

The invention belongs to the technical field of petrochemical organic synthesis, and particularly relates to a preparation method of m-phenylenediamine. According to the invention, m-phthalonitrile isused as a reaction raw material, and m-phenylenediamine is prepared through two steps of reactions of catalytic hydrolysis amidation and Hofmann degradation. According to the method, the key technical problems that in the process of producing m-phenylenediamine through benzene nitration and hydrogenation in a traditional process, due to the fact that dangerous processes of nitration and hydrogenation are involved, potential safety hazards in the production process are large, and the environment is polluted are solved, nitration and hydrogenation reactions are not involved in the process, thereaction temperature is low, reaction is mild, control is easy, the yield reaches 80% or above, and product purity reaches 95% or above.

Preparation method of isophthalimide

The invention belongs to the technical field of tire rubber organic synthesis, and particularly relates to a preparation method of isophthalimide. According to the method, m-phthalonitrile is used asa reaction raw material and is prepared through catalytic hydrolysis of a catalyst in the presence of anhydrous sodium carbonate and hydrogen peroxide. The method does not relate to dangerous processes of nitrification and hydrogenation, solves the problems of large phosphorus-containing wastewater amount and high reaction energy consumption in the traditional dehydration process of isophthalic acid, and has the advantages of environmental protection, safety, reliability, environmental protection and energy saving.