174019-84-2

Basic information

• Product Name: C₂₆H₂₃N₇O₇S
• CAS NO: 174019-84-2
• Molecular Weight: 577.577
• Mol File: 174019-84-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₃N₇O₇S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₃N₇O₇S(174019-84-2)
• EPA Substance Registry System: C₂₆H₂₃N₇O₇S(174019-84-2)

Safety Data

• Hazardous Substances Data: 174019-84-2(Hazardous Substances Data)

Upstream product

• 174019-82-0 1-O-acetyl-5-azido-2,3-di-O-benzoyl-5-deoxy-β-D-ribofuranoside 
• 174019-83-1 4-amino-6-bromo-5-cyano-7-(5-azido-2,3-di-O-benzoyl-5-deoxy-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine 
• 174175-00-9 methyl 5-azido-2,3-di-O-benzoyl-5-deoxy-β-D-ribofuranoside 
• 4099-85-8 ((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 
• 50610-99-6 1-O-methyl-2,3-O-isopropylidene-5-O-(methanesulfonyl)-β-D-ribofuranoside 
• 62819-24-3 methyl 5-azido-5-deoxy-2,3-O-isopropylidene-b-ribofuranoside 
• 35509-22-9 methyl 5-azido-5-deoxy-β-D-ribofuranoside 
• 174019-85-3 4-amino-5-cyano-7-(5-amino-2,3-di-O-benzoyl-5-deoxy-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine 

Relevant articles and documents

Synthesis of 5'-fluoro-5'-deoxy- and 5'-amino-5'-deoxytoyocamycin and sangivamycin and some related derivatives

A series of 5'-substituted analogs of toyocamycin were prepared by condensation of silylated 4-amino-6-bromo-5-cyanopyrrolo[2,3-d]pyrimidine with protected 5-azido-5-deoxy- or 5-fluoro-5-deoxyribofuranose followed by debromination and deblocking. Alternatively, 5'-azido-5'-deoxytoyocamycin was prepared by azidation of toyocamycin. Conversion of the 5-nitrile function of the toyocamycin derivatives into a carboxamide or a thiocarboxamide gave the corresponding analogs of sangivamycin or thiosangivamycin while reduction of the 5'-azido-5'-deoxy nucleosides provided 5'-amino-5'-deoxy derivatives.