174061-36-0Relevant academic research and scientific papers
Stereoselective Amination of Chiral Enolates: Synthesis of enantiomerically pure α,β-Diamino Acids, Chiral Key Compounds in the Synthesis of Conformationally Constrained Peptido- and Non-peptidomimetics
Badorrey, Ramon,Cativiela, Carlos,Diaz-de-Villegas, Maria D.,Galvez, Jose A.
, p. 2787 - 2796 (2007/10/03)
This work describes an efficient synthesis of enantiomerically pure (R)-2-aminomethylalanine, (R)-2-aminomethylnorvaline, (R)-2-aminomethylvaline, (R)-2-aminomethylleucine and (R)-2-aminomethylphenylalanine by electrophilic amination of chiral 2-cyanoeste
Stereoselective Amination of Chiral Enolates: Synthesis of Chiral Key Intermediates for β-Lactam Antibiotics
Cativiela, Carlos,Diaz-de-Villegas, Maria D.,Galvez, Jose A.
, p. 1465 - 1468 (2007/10/02)
Stereoselective enolate trapping of lithium (1S,2R,4R)-1O-dicyclohexylsulfamoylisobornyl-2-cyano-3-phenylpropanoate with O-(diphenylphosphinyl)hydroxylamine followed by appropriate reduction, hydrolysis, and cyclisation processes allows the asymmetric syn
