Welcome to LookChem.com Sign In|Join Free

CAS

  • or
3'-Aminopropiophenone, also known as 3'-aminopropiophenone or 3-Aminopropiophenone, is a chemical compound with the formula C9H11NO. It is a yellowish-brown liquid that is primarily used as an intermediate in the production of pharmaceuticals and other organic compounds. The chemical structure of 3'-aminopropiophenone consists of a benzene ring attached to a propiophenone group with a primary amine (-NH2) functional group located at the 3' position on the benzene ring. This chemical is known for its utility in organic synthesis and can be used as a building block for the preparation of various biologically active compounds. Due to its potential pharmacological and chemical properties, 3'-aminopropiophenone is an important chemical in the field of drug discovery and development.

1197-05-3

Post Buying Request

1197-05-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1197-05-3 Usage

Uses

Used in Pharmaceutical Industry:
3'-Aminopropiophenone is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be a building block for the preparation of biologically active compounds. Its presence in the chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
3'-Aminopropiophenone is used as a key component in organic synthesis for its versatility in forming different chemical entities. Its primary amine functional group enables it to participate in various chemical reactions, making it a valuable precursor in the creation of a wide range of organic compounds.
Used in Drug Discovery and Development:
3'-Aminopropiophenone is utilized as a starting material in drug discovery and development due to its potential pharmacological properties. Researchers can modify its structure to explore new drug candidates with improved efficacy, safety, and pharmacokinetic profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 1197-05-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1197-05:
(6*1)+(5*1)+(4*9)+(3*7)+(2*0)+(1*5)=73
73 % 10 = 3
So 1197-05-3 is a valid CAS Registry Number.

1197-05-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(3-aminophenyl)propan-1-one

1.2 Other means of identification

Product number -
Other names 3-aminopropiophenone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1197-05-3 SDS

1197-05-3Relevant articles and documents

Preparation method of high-temperature-resistant composite cross-linking agent

-

Paragraph 0044; 0055; 0061; 0072; 0078; 0089; 0095; 0106, (2021/06/22)

The invention belongs to the technical field of preparation of crosslinking agents, and particularly relates to a preparation method of a high-temperature-resistant composite crosslinking agent, which comprises 20 - 40 parts of a zirconium oxychloride sol

Selective Cross-Coupling of (Hetero)aryl Halides with Ammonia to Produce Primary Arylamines using Pd-NHC Complexes

Lombardi, Christopher,Day, Jonathan,Chandrasoma, Nalin,Mitchell, David,Rodriguez, Michael J.,Farmer, Jennifer L.,Organ, Michael G.

supporting information, p. 251 - 254 (2017/04/26)

Herein we report the first example of (hetero)arylation of ammonia using a monoligated palladium-NHC complex. The new, rationally designed, precatalyst (DiMeIHeptCl)Pd(allyl)Cl featuring highly branched alkyl chains has been shown to be effective in selective aminations across a range of challenging substrates, including nitrogen-containing heterocycles and those featuring base-sensitive functionality. The less bulky Pd-PEPPSI-IPentCl precatalyst performs well for ortho-substituted aryl halides, giving monoarylated products in high yield with good selectivity.

Palladium-catalyzed coupling of ammonia with aryl chlorides, bromides, iodides, and sulfonates: A general method for the preparation of primary arylamines

Vo, Giang D.,Hartwig, John F.

supporting information; scheme or table, p. 11049 - 11061 (2009/12/05)

We report that the complex generated from Pd[P(o-tol)3] 2 and the alkylbisphosphine CyPF-t-Bu is a highly active and selective catalyst for the coupling of ammonia with aryl chlorides, bromides, iodides, and sulfonates. The couplings of ammonia with this catalyst conducted with a solution of ammonia in dioxane form primary arylamines from a variety of aryl electrophiles in high yields. Catalyst loadings as low as 0.1 mol % were sufficient for reactions of many aryl chlorides and bromides. In the presence of this catalyst, aryl sulfonates also coupled with ammonia for the first time in high yields. A comparison of reactions in the presence of this catalyst versus those in the presence of existing copper and palladium systems revealed a complementary, if not broader, substrate scope. The utility of this method to generate amides, imides, and carbamates is illustrated by a one-pot synthesis of a small library of these carbonyl compounds from aryl bromides and chlorides, ammonia, and acid chlorides or anhydrides. Mechanistic studies show that reactions conducted with the combination of Pd[P(o-tol)3]2 and CyPF-t-Bu as catalyst occur with faster rates and higher yields than those conducted with CyPF-t-Bu and palladiun(II) as catalyst precursors because of the low concentration of active catalyst that is generated from the combination of palladium(II), ammonia, and base.

Non-peptidic HIV protease inhibitors: C2-symmetry-based design of bis- sulfonamide dihydropyrones

Janakiraman, Musiri N.,Watenpaugh, Keith D.,Tomich, Paul K.,Chong, Kong-Teck,Turner, Steve R.,Tommasi, Ruben A.,Thaisrivongs, Suvit,Strohbach, Joseph W.

, p. 1237 - 1242 (2007/10/03)

Potent, non-peptidic, dihydropyrone sulfonamide HIV protease inhibitors have been previously described. Crystallographic analysis of dihydropyrone sulfonamide inhibitor/HIV protease complexes suggested incorporation of a second, C2 symmetry-rel

PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS

-

, (2008/06/13)

The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R 10 and R 20 taken together are formulae (III) and (IV). STR1

Facile Hydrodehalogenation with H2 and Pd/C Catalyst under Multiphase Conditions. 2. Selectivity and Kinetics

Marques, Carlos Alberto,Selva, Maurizio,Tundo, Pietro

, p. 3830 - 3837 (2007/10/02)

Hydrodehalogenation of polyhalogenated aromatics with Pd/C catalyst carried out in the presence of a quaternary onium salt follows zero-order kinetics in the substrate and first-order kinetics in the Pd/C catalyst; the related rate constants were determined for o-, m- and p-bromotoluenes, o-, m- and p-chloroalkylbenzenes (methyl, ethyl, and propyl derivatives), and other aryl halides.Reaction rates, depending on the aromatic to be reduced, may be strongly enhanced by the presence of quaternary onium salts: the isomeric chloroethylbenzenes were reduced 50 times faster when operating in the presence of Aliquat 336 (1).Also the hindered 2-chloro-m-xylene easily yielded m-xylene.The cocatalyst onium salts operate by being adsorbed on the Pd/C surface, as shown when kinetic constants are reported by varying the onium salt amount: classical Langmuir adsorption isotherms are observed.The presence of the onium salt may also influence selectivity in the reduction of isomeric aryl halides: when 1 is present, p-dichlorobenzene reacts in diethyl ether at 20 deg C, 5-fold slower than the ortho isomer; whereas the reduction rates of the two compounds are almost the same in its absence.

3' Cyanophenylalkanolamines: a contribution to the search for selective β adrenomimetic compounds

Pratesi,Grana,Villa

, p. 753 - 765 (2007/10/06)

Some derivatives of 1 (3' cyanophenyl) 2 aminoethanol have been synthesized in which OH is substituted at the nucleus, methyl or ethyl at the α carbon atom and isopropyl or t butyl at the nitrogen atom. The pharmacological research has shown that by combi

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1197-05-3