17413-79-5

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-Chlorophenoxy)-2-methylpropionic acid is used as a nonsteroidal anti-inflammatory drug (NSAID) for its ability to reduce pain and inflammation. It is particularly effective in treating conditions that involve swelling and discomfort, making it a valuable component in various medications aimed at alleviating such symptoms.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(2-Chlorophenoxy)-2-methylpropionic acid serves as a key intermediate in the synthesis of various compounds. Its role in this industry is pivotal for the development of products that can enhance crop protection and improve agricultural yields.
Used in Organic Compounds Synthesis:
2-(2-Chlorophenoxy)-2-methylpropionic acid is utilized as a building block in the synthesis of a range of organic compounds. Its structural attributes make it a suitable candidate for creating new molecules with potential applications across different fields, thereby expanding its utility in chemical research and development.
Used in Pharmaceutical Research:
As a component in pharmaceutical research, 2-(2-Chlorophenoxy)-2-methylpropionic acid aids scientists in exploring its potential for developing new drugs and therapies. Its anti-inflammatory nature positions it as a candidate for further studies aimed at understanding its mechanisms and optimizing its efficacy in treating inflammatory conditions.

InChI:InChI=1/C10H11ClO3/c1-10(2,9(12)13)14-8-6-4-3-5-7(8)11/h3-6H,1-2H3,(H,12,13)

Upstream product

• 600-00-0 ethyl 2-bromoisobutyrate 
• 1193-00-6 sodium 4-chlorophenolate 
• 95-57-8 2-monochlorophenol 
• 2052-01-9 2-bromo-2-methylpropionic acid 

Downstream Products

• 59227-81-5 ethyl 2-(2-chlorophenoxy)-2-methylpropionate 
• 76410-72-5 α-(2-chloro-phenoxy)-isobutyric acid amide 
• 4878-09-5 2-(2-chlorophenoxy)-2-methylpropionyl chloride 
• 58327-16-5 2-(2-Chloro-phenoxy)-2-methyl-propionic acid 3,3,5-trimethyl-cyclohexyl ester 
• 116762-29-9 2-(2-chlorophenoxy)-2-methyl-propionyl-cyanomethylenetriphenylphosphorane 

Relevant academic research and scientific papers

Liquid-phase synthesis of 2-methyl-2-aryloxypropanoic acid derivatives from poly(ethylene glycol) supported 2-bromo-2-methylpropanoate

An efficient liquid-phase synthesis of 2-methyl-2-aryloxypropanoic acid derivatives with good yields and high purity on soluble polyethylene glycol (PEG) has been developed by treatment of PEG-bound 2-bromo-2-methylpropanoate with phenoxides in the presence of a catalytic amount of NBu4I and KI, and subsequent cleavage from the PEG.

Improved method for the synthesis of 2-methyl-2-aryloxypropanoic acid derivatives

An improved method for the formation of 2-methyl-2-aryloxypropanoic acid derivatives, an important class of compounds for the potential treatment of type II diabetes, is reported. This method offers several advantages over the existing chemistry for this transformation.

Pd(II)-catalyzed ortho - Or meta-C-H olefination of phenol derivatives

A combination of weakly coordinating auxiliaries and ligand acceleration allows for the development of both ortho- and meta-selective C-H olefination of phenol derivatives. These reactions demonstrate the feasibility of directing C-H functionalizations when functional groups are distal to target C-H bonds. The meta-C-H functionalization of electron-rich phenol derivatives is unprecedented and orthogonal to previous electrophilic substitution of phenols in terms of regioselectivity. These methods are also applied to functionalize α-phenoxyacetic acids, a fibrate class of drug scaffolds.

INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME

The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatme