174149-75-8

Upstream product

• 174149-61-2 (1R,2S,3S,4S)-1-O-benzyl-2,3-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 56745-67-6 (4S)-4-tert-butyldimethylsilyloxycyclopent-2-en-1-one 
• 174149-59-8 (1R,2S,3S,4S)-1-O-benzyl-4-O-(tert-butyldimethylsilyl)-2,3-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-58-7 (1R,2R,3S,4S)-1-O-benzyl-4-O-(tert-butyldimethylsilyl)cyclopentane-1,2,3,4-tetrol 
• 174149-57-6 (1R,4S)-1-O-benzyl-4-O-(tert-butyldimethylsilyl)cyclopent-2-ene-1,4-diol 
• 120520-91-4 (1R,4S)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enol 
• 216015-22-4 (3aS,4R,6aR)-2,2-dimethyl-2H,3aH,4H,6aH-cyclopenta[d][1,3]-dioxol-4-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 174149-80-5 (1S,2S,3R,4R,5S)-2-O-benzyl-5-((tert-butoxycarbonyl)amino)-1-O-(tert-butyldimethylsilyl)-3,4-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-79-2 (1S,2S,3R,4R,5S)-5-azido-2-O-benzyl-1-O-(tert-butyldimethylsilyl)-3,4-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-81-6 (1S,2S,3R,4R,5R)-2-O-benzyl-5-((tert-butoxycarbonyl)amino)-3,4-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-84-9 (3aR,3bR,6aS,7R,7aS)-7-benzoxy<1,3,2>dioxathiolo<4,5-a>cyclopent<4,5-d>oxazolidin-2,2,5-trione 
• 174149-78-1 (1R,2S,3S,4S,5R)-2-O-benzyl-1-O-(tert-butyldimethylsilyl)-5-iodo-3,4-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-82-7 (3aR,3bS,6aR,7R,7aR)-7-benzoxy-2,2-dimethyl<1,3>dioxolo<4,5-a>cyclopent<4,5-d>oxazolidin-5-one 
• 174149-83-8 (3aR,4R,5R,6R,7aS)-6-benzoxy-4,5-dihydroxycyclopentoxazolidin-5-one 
• 174149-77-0 (1R,2S,3S,4S,5S)-2-O-benzyl-5-iodo-3,4-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-76-9 (1R,2S,3S,4S,5R)-1-O-acetyl-2-O-benzyl-5-iodo-3,4-O-isopropylidenecyclopentane-1,2,3,4-tetrol 

Relevant academic research and scientific papers

Chiral syntheses of 6′-β-fluoroaristeromycin, 6′-β-fluoro-5′-noraristeromycin and aristeromycin

Carbocyclic nucleosides substituted at the C-6′ position are receiving increasing attention. Chiral synthetic accessibility to the biologically promising 6′-β-fluoroaristeromycin is lacking. Its preparation and that of the 5′-nor analogue are described. A

Flexible enantiodivergent synthesis and biological activity of mannostatin analogues, new cyclitol glycosidase inhibitors

Mannostatin A (1) is a new cyclitol inhibitor of glycoprotein processing. 2-Epimannostatin A (12) and its enantiomer (13) as well as their positional isomers (14, 15) were designed for probing structure-activity relationships in this class of glycosidase inhibitors. The analogues have been synthesized from (S)-4-((tert-butyldimethylsilyl)oxy)-2-cyclopentenone by an enantiodivergent strategy in a totally stereospecific fashion. Compound 13 showed inhibition against almond β-glucosidase and is shown to be a topographical analogue of β-D-glucopyranoside.