174153-23-2

Upstream product

• 1883-75-6 2,5-bis-(hydroxymethyl)furan 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 222967-29-5 (1S,4R)-1,4-Bis-benzyloxymethyl-7-oxa-bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid dimethyl ester 
• 222967-31-9 (1R,2R,4S,5S,6R,7S)-1,5-Bis-benzyloxymethyl-6,7-dihydroxy-3,8-dioxa-tricyclo[3.2.1.0^2,4]octane-6,7-dicarboxylic acid dimethyl ester 
• 222967-30-8 (1R,2R,4S,5S)-1,5-Bis-benzyloxymethyl-3,8-dioxa-tricyclo[3.2.1.0^2,4]oct-6-ene-6,7-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

A new synthetic route for construction of the core of Zaragozic acids

A new synthetic route for construction of the core moiety of zaragozic acids from 2,5-furandimethanol (2) is described. This synthesis involves highly stereocontrolled transformation of 2 into 7-oxabicyclo[2.2.1]heptane derivative 13, and the Grob fragmentation-reduction-iodo acetalization reaction (one-pot process) of 13 as a key step to give 16.

Coupling focused microwaves and solvent-free phase transfer catalysis : Application to the synthesis of new furanic diethers

A new family of furanic ethers was obtained by alkylation of 2,5-furandimethanol or furfuryl alcohol under microwave in phase transfer catalysis (PTC) conditions in the absence of solvent. Products were synthesized in good yields (> 80 %) within 10 min or