222967-30-8Relevant articles and documents
A new synthetic route for construction of the core of Zaragozic acids
Koshimizu, Haruta,Baba, Tomo,Yoshimitsu, Takehiko,Nagaoka, Hiroto
, p. 2777 - 2780 (2007/10/03)
A new synthetic route for construction of the core moiety of zaragozic acids from 2,5-furandimethanol (2) is described. This synthesis involves highly stereocontrolled transformation of 2 into 7-oxabicyclo[2.2.1]heptane derivative 13, and the Grob fragmentation-reduction-iodo acetalization reaction (one-pot process) of 13 as a key step to give 16.