174156-40-2

Upstream product

• 697751-93-2 (2R,3R)-3-(tert-butyldiphenylsilyloxy)-2-methylbutanal 
• 697751-91-0 (E)-(4S,5R)-5-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-hex-2-en-1-ol 

Downstream Products

• 174156-41-3 (E)-(2R,3S,6S,7R)-7-(tert-Butyl-diphenyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,6-dimethyl-oct-4-enoic acid methyl ester 
• 174156-45-7 Acetic acid (3E,15E)-(1R,2S,5S,6R,10S,12R,14S)-14-(tert-butyl-dimethyl-silanyloxy)-16-ethyl-5-(4-methoxy-benzyloxy)-1,2,6,10,12-pentamethyl-7-oxo-octadeca-3,15,17-trienyl ester 
• 174156-46-8 Benzoic acid (3E,15E)-(1R,2S,5S,6R,10S,12R,14S)-14-(tert-butyl-dimethyl-silanyloxy)-16-ethyl-5-(4-methoxy-benzyloxy)-1,2,6,10,12-pentamethyl-7-oxo-octadeca-3,15,17-trienyl ester 

Relevant academic research and scientific papers

Determination of the C-7,9,12,13,17 and 18 stereochemistries of tautomycetin. Synthesis of the tautomycetin degradation product

Syntheses of the degradation product 3 of tautomycetin (1) and its diastereoisomers have been achieved. Comparison of the spectral data of these diastereoisomers with those of the degradation product of natural 1 indicates that tautomycetin has the 7R,9S,12S,13S,17S,18R stereochemistry.