174355-17-0

Basic information

• Product Name: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one
• Synonyms: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one
• CAS NO: 174355-17-0
• Molecular Weight: 287.434
• Mol File: 174355-17-0.mol

Chemical Properties

• CAS DataBase Reference: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one(174355-17-0)
• EPA Substance Registry System: 3-Benzyloxy-2-methyl-1-trimethylsilanyl-1H-pyridin-4-one(174355-17-0)

Safety Data

• Hazardous Substances Data: 174355-17-0(Hazardous Substances Data)

Upstream product

• 61160-18-7 3-benzyloxy-2-methyl-1H-pyridin-4-one 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 61049-69-2 3-O-benzylmaltol 
• 118-71-8 Maltol 

Downstream Products

• 174355-18-1 Acetic acid (2R,3R,4R,5R)-4,5-diacetoxy-2-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-tetrahydro-pyran-3-yl ester 
• 87597-94-2 1-β-D-ribofuranosyl-3-hydroxy-2-methyl-4-pyridone 
• 654054-85-0 3-Hydroxy-1-((2R,5S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-methyl-1H-pyridin-4-one 
• 654054-85-0 3-Hydroxy-1-((2S,5S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-methyl-1H-pyridin-4-one 
• 654054-82-7 (1'S,4'S)-1-[5'-tert-butyldiphenylsilyl-2',3'-dideoxy-α-D-ribofuranosyl]-2-methyl-3-benzyloxy-4-pyridinone 
• 654054-81-6 (1'R,4'S)-1-[5'-tert-butyldiphenylsilyl-2',3'-dideoxy-β-D-ribofuranosyl]-2-methyl-3-benzyloxy-4-pyridinone 
• 174355-19-2 C₃₉H₃₃NO₉ 

Relevant articles and documents

Synthesis and antiviral evaluation of 3-hydroxy-2-methylpyridin-4-one dideoxynucleoside derivatives

We describe the synthesis and the antiviral evaluation of novel α and β dideoxynucleoside derivatives in which the base has been replaced by a 3-hydroxy-2-methylpyridin-4-one. The syntheses were successfully achieved by the use of the standard Vorbrueggen coupling conditions. Moderate activity of these compounds were found on herpes simplex virus (HSV) type 1 and type 2.

Compositions and methods for chelation therapy

The invention relates to compositions and methods of treatment using an iron chelator, an antioxidant, estrogen, and/or combinations thereof, optionally, linked to a nanoparticle, to treat a subject in need thereof. The compositions and methods may be used to restore or protect the normal functions of osteoblast and osteoclast by depleting iron and inhibiting oxidative damage. The compositions and methods may also be used to increase the bone formation rate in a subject.

Efficient synthesis of N-[(2-hydroxyethoxy) methyl]-2-alkyl-3-hydroxy-4-pyridinone by a modified Hilbert-Johnson reaction

Ethyleneglycol derivatives of 2-methyl (and ethyl)-3-hydroxy-4-pyridinone were synthesized by a modified Hilbert-Johnson reaction. The synthesis proceeds by reaction of O-protected 2-alkyl-3-hydroxy-4-pyridinone with hexamethyldisilazane in the presence o

Synthesis of 2-alkyl-3-hydroxy-4-pyridinone-ribonucleosides, potential oral iron chelators

Several ribonucleosides, named 2-alkyl-3-hydroxy-1-(β-D-ribofuranosyl or pyranosyl)-4-pyridinones, were synthesized in good yield. The method provides a useful means to obtain α-ketohydroxypyridin derivatives with different sugar moieties that, if used as