174468-55-4

Basic information

• Product Name: F90103
• Synonyms: 4-Fluoro-5-(4-methylpiperazin-1-yl)benzene-1,2-diamine;F90103
• CAS NO: 174468-55-4
• Molecular Formula: C₁₁H₁₇FN₄
• Molecular Weight: 224.281
• Mol File: 174468-55-4.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: F90103(CAS DataBase Reference)
• NIST Chemistry Reference: F90103(174468-55-4)
• EPA Substance Registry System: F90103(174468-55-4)

Safety Data

• Hazardous Substances Data: 174468-55-4(Hazardous Substances Data)

Usage

General Description

F90103 is a chemical compound used as a corrosion inhibitor in petroleum production and refining. It is a water-soluble organic compound that helps protect metal surfaces from the damaging effects of corrosion caused by water, oxygen, and other corrosive elements. F90103 is often used in the oil and gas industry to protect pipelines, storage tanks, and other equipment from rust and deterioration. It is effective at low concentrations and can be added directly to the process or storage systems where corrosion protection is needed. F90103 is also used in other industrial applications where metal corrosion is a concern, making it a valuable tool for maintaining the integrity of metal structures and equipment.

Upstream product

• 82759-10-2 4-fluoro-5-(4-methylpiperazin-1-yl)-2-nitrobenzenamine 
• 109-01-3 1-methyl-piperazine 
• 104222-34-6 2-nitro-4-fluoro-5-chloroaniline 
• 78056-39-0 4,5-difluoro-2-nitroaniline 
• 1393681-47-4 5-fluoro-1-amino-4-(4-methylpiperazino)-2-nitrobenzene 
• 877-90-7 N-(3-chloro-4-fluorophenyl)acetamide 

Downstream Products

• 174468-59-8 4-Fluoro-5-(4-methyl-piperazin-1-yl)-N²-[1-phenyl-meth-(E)-ylidene]-benzene-1,2-diamine 
• 1224937-86-3 (Z)-8-fluoro-7-(4-methylpiperazino)-3-phenyl-1-phenylimino-thiazolo[3,4-a]quinoxalin-4(5H)-one 
• 1224937-88-5 (Z)-7-fluoro-8-(4-methylpiperazino)-3-phenyl-1-phenyliminothiazolo[3,4-a]-quinoxalin-4(5H)-one 
• 1393681-36-1 7-(4-methylpiperazin-2-yl)-8-fluoro-3-phenyl-1-phenyliminothiazolo[3,4-a]quinoxalin-4(5h)-one 
• 1393681-35-0 7-fluoro-8-(4-methylpiperazin-2-yl)-3-phenyl-1-phenyliminothiazolo[3,4-a]quinoxalin-4(5H)-one 
• 174468-63-4 N²-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-4-fluoro-5-(4-methyl-piperazin-1-yl)-benzene-1,2-diamine 

Relevant articles and documents

Synthesis of new 2-ferrocenyl-5-fluoro-6-(4-substituted-1-piperazinyl)-1H- benzimidazoles of potential biological interest

New substituted 2-ferrocenylbenzimidazole derivatives are prepared by the oxidation of corresponding Schiffs bases in situ, generated from corresponding 1,2-diamino-4-fluoro-5-(1-piperazinyl)benzenes and 2-ferrocenecarboxaldehyde using nitrobenzene.

Chemo-enzymatic synthesis and biological evaluation of 5,6-disubstituted benzimidazole ribo- and 2′-deoxyribonucleosides

A number of new 5,6-disubstituted benzimidazoles have been prepared and their substrate properties for recombinant E. coli purine nucleoside phosphorylase (PNP; the product of the deoD gene) in the transglycosylation reaction were investigated. The heterocyclic bases showed good substrate activity for PNP and the ribo- and 2-deoxyribonucleosides were synthesized. The predominant (OMe and OEt) or exclusive (Oi-Pr, morpholino, and N-methylpiperazino) formation of the 5-substituted 6-fluoro-1-(β-d- ribofuranosyl)benzimidazoles was observed. The formation of the regioisomeric 6- methoxy-, 6-ethoxy-, or 6-isopropoxy-substituted 1-(2-deoxy-β-d- ribofuranosyl)-5-fluorobenzimidazoles was observed in the trans-2- deoxyribosylation reaction of the corresponding bases. The predominant or exclusive formation of the regioisomeric N1-nucleosides with bulky 5-substituents of 6-fluorobenzimidazole points to a large hydrophobic pocket in the E. coli PNP active site that can accommodate these groups. The biological activity of the synthesized nucleosides was studied and revealed no inhibitory activity against a broad variety of DNA and RNA viruses. The compounds also lacked significant cytotoxicity. Georg Thieme Verlag Stuttgart New York.

Synthesis of benzimidazoles as antimicrobial agents

Suitably substituted o-phenylenediamines on treatment with S-methyl isothiourea and methyl chloroformate gave different benzimidazole carbamates (14-19).