174485-82-6

Basic information

• Product Name: 5-NITRO-PYRIDINE-2-SULFONYL CHLORIDE
• Synonyms: 5-NITRO-PYRIDINE-2-SULFONYL CHLORIDE
• CAS NO: 174485-82-6
• Molecular Formula: C₅H₃ClN₂O₄S
• Molecular Weight: 222.61
• Mol File: 174485-82-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 372.5±27.0 °C(Predicted)
• Appearance: /
• Density: 1.697±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -9.17±0.29(Predicted)
• CAS DataBase Reference: 5-NITRO-PYRIDINE-2-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-NITRO-PYRIDINE-2-SULFONYL CHLORIDE(174485-82-6)
• EPA Substance Registry System: 5-NITRO-PYRIDINE-2-SULFONYL CHLORIDE(174485-82-6)

Safety Data

• Hazardous Substances Data: 174485-82-6(Hazardous Substances Data)

Usage

Uses

5-Nitropyridine-2-sulfonyl chloride is a useful reagent in the synthesis of hydroxypyrone derivatives with HIV protease inhibitory properties.

Upstream product

• 2127-09-5 2-mercapto-5-nitropyridine 
• 2127-10-8 5,5'-dinitro-2,2'-disulfanediyl-bis-pyridine 

Downstream Products

• 318479-62-8 5-nitro-pyridine-2-sulfonic acid (3-{2-[5-(cyclopropyl-phenyl-methyl)-4-hydroxy-6-oxo-6H-pyran-2-yl]-butyl}-phenyl)-amide 

Relevant articles and documents

BORON-CONTAINING SMALL MOLECULES

This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.

PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R 10 and R 20 taken together are formulae (III) and (IV). STR1