174498-02-3Relevant articles and documents
Carbocyclic analogues of the potent cytidine deaminase inhibitor 1-(β- D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (zebularine)
Jeong, Lak Shin,Buenger, Greg,McCormack, John J.,Cooney, David A.,Hao, Zhang,Marquez, Victor E.
, p. 2572 - 2578 (1998)
Three carbocylic analogues of the potent cytidine deaminase inhibitor (CDA) zebularine [1-(β-D-ribofuranosyl)-l,2-dihydropyrimidin-2-one, 1a] were synthesized. The selected pseudosugar templates correspond, respectively, to the cyclopentenyl moiety of nep
4',1'a-METHANOCARBOCYCLIC ADENOSINE ANALOGUES AS POTENTIAL INHIBITORS OF S-ADENOSYLHOMOCYSTEINE HYDROLASE
Jeong, Lak S.,Marquez, Victor E.,Yuan, Chong-Shen,Borchardt, Ronald T.
, p. 2651 - 2656 (2007/10/03)
Cyclopropane-fused carbocyclic adenosine (4) and its 5'-carboxaldehyde analogue (5) were synthesized as potential inhibitors of S-adenosylhomocysteine hydrolase.The key bicyclohexane alcohol (8) was obtained from the optically pure cyclopentenone s