17459-75-5Relevant academic research and scientific papers
Aminolysis of Y-substituted phenyl X-substituted benzoates with piperidine: Effect of nonleaving group substituent
Um, Ik-Hwan,Lee, Ji-Youn,Ko, Seung-Hak,Bae, Sun-Kun
, p. 5800 - 5803 (2007/10/03)
The title reaction has been suggested to proceed through a zwitterionic tetrahedral intermediate with a change in the rate determining step on the basis of the curved Bronsted-type plots obtained. The curvature center of the curved Bronsted-type plots is at pKa = 6.4 regardless of the electronic nature of the substituent X in the benzoyl moiety.
