174672-06-1

Basic information

• Product Name: 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
• Synonyms: 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole;AN-2718;5-Chloro-1,3-dihydro-2,1-benzoxaborol-1-ol, 95%
• CAS NO: 174672-06-1
• Molecular Formula: C7H6BClO2
• Molecular Weight: 168.38534
• Product Categories: API
• Mol File: 174672-06-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 150-154 °C
• Boiling Point: 273.2±50.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• PKA: 6.60±0.20(Predicted)
• CAS DataBase Reference: 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole(174672-06-1)
• EPA Substance Registry System: 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole(174672-06-1)

Safety Data

• Hazardous Substances Data: 174672-06-1(Hazardous Substances Data)

Usage

General Description

5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole is a chemical compound that belongs to the class of benzoxaboroles, which are known for their various biological activities. This particular compound has a chlorine atom at the 5th position on the benzene ring and a hydroxyl group attached to the boron atom. It has been studied for its potential use as a pharmaceutical agent, showing promising activity against a variety of pathogens, including bacteria and fungi. The unique structure and reactivity of 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole make it a valuable target for medicinal chemistry research, with potential applications in the development of new drugs for the treatment of infectious diseases.

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Relevant articles and documents

FLOW REACTION PROCESS FOR MANUFACTURE OF BORON-CONTAINING AGROCHEMICALS

The present invention relates to methods of preparing benzoxaboroles. Benzoxaborole compounds have shown promise as antimicrobial agents, especially against fungal pathogens. The invention also relates to compositions of acyclic alkoxy boronic acid esters as intermediates, and continuous flow processes of mixing the intermediates with organomagnesium, magnesium, or organolithium reagents to form the desired benzoxaboroles.

BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS

Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.

Compounds for the Treatment of Periodontal Disease

Compounds, compositions and methods are provided which are useful in the treatment of periodontal disease.