174874-19-2

Upstream product

• 98-88-4 benzoyl chloride 
• 174874-18-1 (2S,6S,7R)-(3E)-9-t-butyldimethylsilyloxy-6,7-epoxy-1-p-methoxyphenylmethoxynon-3-en-2-ol 
• 174874-17-0 (2S,6S,7R)-9-t-butyldimethylsilyloxy-6,7-epoxy-1-p-methoxyphenylmethoxynon-3-yn-2-ol 

Downstream Products

• 174874-22-7 (2S,6R,7R)-(3E)-2-benzoyloxy-6-bromo-7-t-butyldimethylsilyloxy-1-p-methoxyphenylmethoxynon-3-en-9-ol 9-pivaloate 
• 174874-21-6 (2S,6R,7R)-(3E)-2-benzoyloxy-6-bromo-1-p-methoxyphenylmethoxynon-3-ene-7,9-diol 9-pivaloate 
• 143660-63-3 (2S,6R,7R)-(3E)-2-benzoyloxy-6-bromo-1-p-methoxyphenylmethoxynon-3-ene-7,9-diol 
• 143660-64-4 (2S,6R,7R)-(3E)-6-bromo-7-t-butyldimethylsilyloxy-1-p-methoxyphenylmethoxynon-3-ene-2,9-diol 9-pivaloate 
• 143660-62-2 (2S,6S,7R)-(3E)-6,7-epoxy-1-p-methoxyphenylmethoxynon-3-ene-2,9-diol 2-benzoate 

Relevant academic research and scientific papers

Total synthesis of (-)-dactylynes

The first total synthesis of (-)-dactylyne (1) and (-)-isodactylyne (2), which have been isolated from sea hare, is described in detail. Critical steps in the synthesis include a stereoselective construction as well as an intramolecular ring closure of 32, and the effective double elongation reactions (59 → 63 and 64, 67 → 68, and 70 → 71).