174955-26-1Relevant articles and documents
Enantioselective synthesis of the four isomers of the biologically active metabolite of the 2-arylpropanoic acid NSAID, ximoprofen, and assessment of their inhibitory activity on human platelet cyclo-oxygenase in vitro
Hamon,Hayball,Massy-Westropp,Newton,Tamblyn
, p. 263 - 272 (1996)
The four stereoisomers of the parent keto acid of the oximino drug ximoprofen have been prepared in high enantiomeric purity. The stereochemistry in the propionic acid chain was established by the combinatin of Sharpless epoxidation followed by stereosele