174955-24-9Relevant articles and documents
Enantioselective synthesis of the four isomers of the biologically active metabolite of the 2-arylpropanoic acid NSAID, ximoprofen, and assessment of their inhibitory activity on human platelet cyclo-oxygenase in vitro
Hamon,Hayball,Massy-Westropp,Newton,Tamblyn
, p. 263 - 272 (2007/10/03)
The four stereoisomers of the parent keto acid of the oximino drug ximoprofen have been prepared in high enantiomeric purity. The stereochemistry in the propionic acid chain was established by the combinatin of Sharpless epoxidation followed by stereosele
Concerning the enantioselective synthesis of the isomers of the arylpropanoic acid NSAID ximoprofen
Hamon, David P.G.,Massy-Westropp, Ralph A.,Newton, Josephine L.
, p. 1079 - 1082 (2007/10/02)
All four stereoisomers of the parent ketone of the oximido drug ximoprofen have been prepared pure. An attempt to isolate the pure E and Z isomers of the oxime derivative from one of these stereoisomers was unsuccessful.