175-94-0 Usage
General Description
2-Azaspiro[4.4]nonane is a chemical compound with a unique spirocyclic structure containing a nitrogen atom and a bicyclic nonane ring. It is most commonly used in the pharmaceutical industry as a structural motif for the development of new drugs. The compound has potential applications in the synthesis of various pharmaceuticals, including those used in the treatment of central nervous system disorders such as schizophrenia and anxiety. 2-Azaspiro[4.4]nonane has also shown potential as a chiral building block in the synthesis of biologically active compounds, making it an important component in the development of new therapeutic agents. The compound’s unique structure and versatile applications make it an important target for research and development in the pharmaceutical field.
Check Digit Verification of cas no
The CAS Registry Mumber 175-94-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,7 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 175-94:
(5*1)+(4*7)+(3*5)+(2*9)+(1*4)=70
70 % 10 = 0
So 175-94-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H15N/c1-2-4-8(3-1)5-6-9-7-8/h9H,1-7H2
175-94-0Relevant articles and documents
Radical cyclizations of cyclic ene sulfonamides occur with β-elimination of sulfonyl radicals to form polycyclic imines
Zhang, Hanmo,Hay, E. Ben,Geib, Steven J.,Curran, Dennis P.
, p. 16610 - 16617 (2013/12/04)
Radical cyclizations of cyclic ene sulfonamides provide stable bicyclic and tricyclic aldimines and ketimines in good yields. Depending on the structure of the precursor, the cyclizations occur to provide fused and spirocyclic imines with five-, six-, and seven-membered rings. The initial radical cyclization produces an α-sulfonamidoyl radical that undergoes elimination to form the imine and a phenylsulfonyl radical. In a related method, 3,4-dihydroquinolines can also be produced by radical translocation reactions of N-(2- iodophenylsulfonyl)tetrahydroiso-quinolines. In either case, very stable sulfonamides are cleaved to form imines (rather than amines) under mild reductive conditions.
