17512-70-8

Basic information

• Product Name: 2-fluoro-N-hydroxybenzamide
• CAS NO: 17512-70-8
• Molecular Formula: C₇H₆FNO₂
• Molecular Weight: 155.1264
• Mol File: 17512-70-8.mol
• Article Data: 8

Chemical Properties

• Density: 1.349g/cm³
• Refractive Index: 1.552
• CAS DataBase Reference: 2-fluoro-N-hydroxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-N-hydroxybenzamide(17512-70-8)
• EPA Substance Registry System: 2-fluoro-N-hydroxybenzamide(17512-70-8)

Safety Data

• Hazardous Substances Data: 17512-70-8(Hazardous Substances Data)

Usage

General Description

2-fluoro-N-hydroxybenzamide is a chemical compound with the molecular formula C7H6FNO2. It is a derivative of benzamide, with a fluorine atom and a hydroxyl group attached to the benzene ring. 2-fluoro-N-hydroxybenzamide is often used in organic synthesis and pharmaceutical research, as it can be utilized as a building block for creating new chemical structures. It has also been studied for its potential biological activities and applications, including its potential as a drug candidate for treating various diseases. 2-fluoro-N-hydroxybenzamide may have implications in the development of new medications and chemical processes due to its unique structure and properties.

Upstream product

• 445-29-4 o-fluoro-benzoic acid 
• 393-52-2 2-Fluorobenzoyl chloride 
• 394-35-4 methyl 2-fluorobenzoate 

Downstream Products

• 391-07-1 2-(2-fluorophenyl)-5-phenyloxazole 
• 18595-84-1 2-(2-fluorophenyl)-4H-benzo[d][1,3]oxazin-4-one 
• 824-48-6 N-(2-fluorophenyl)formamide 

Relevant articles and documents

A new method for preparing N-acyloxaziridines via tandem O, N-addition of hydroxamic acids to methyl propiolate.

N-Acyloxaziridines were prepared from a tandem O, N-addition of hydroxamic acids to metyl propiolate in the presence of 4-methyl morpholine as a catalyst in good to excellent yields.

Rhodium(III)-catalyzed C4-amidation of indole-oximes with dioxazolones: Via C-H activation

A novel method for the Rh(III)-catalyzed oxime-directed C-H amidation of indoles with dioxazolones has been developed. This strategy provides an exclusive site selectivity and the directing group can be easily removed. This transformation features a wide substrate scope, good functional group tolerance and excellent yields, and may serve as a significant tool to construct structurally diverse indole derivatives for the screening of potential pharmaceuticals in the future. This journal is

Synthesis of 2,5-disubstituted oxazoles: Via cobalt(III)-catalyzed cross-coupling of N -pivaloyloxyamides and alkynes

An efficient synthesis of 2,5-disubstituted oxazoles via Co(iii) catalysis is described herein. The synthesis is achieved under mild conditions through [3+2] cycloaddition of N-pivaloyloxyamides and alkynes. The reaction operates through an internal oxidation pathway and features a very broad substrate scope. The one-step synthesis of natural products such as texamine and balsoxin has been demonstrated via this protocol.