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17512-88-8

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17512-88-8 Usage

General Description

The chemical compound ({[(4-methylphenyl)sulfonyl]oxy}imino)(phenyl)acetonitrile is an organic compound consisting of a nitro group, a sulfonyl group, and an acetonitrile group. It is a sulfonamide derivative, and is commonly used in pharmaceutical and chemical research. ({[(4-methylphenyl)sulfonyl]oxy}imino)(phenyl)acetonitrile is mainly utilized as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as an intermediate in the production of organic compounds. The compound has potential applications in medicinal chemistry, particularly in the development of new drugs. Overall, ({[(4-methylphenyl)sulfonyl]oxy}imino)(phenyl)acetonitrile is a versatile compound with a range of potential uses in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 17512-88-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,5,1 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17512-88:
(7*1)+(6*7)+(5*5)+(4*1)+(3*2)+(2*8)+(1*8)=108
108 % 10 = 8
So 17512-88-8 is a valid CAS Registry Number.

17512-88-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [(E)-[cyano(phenyl)methylidene]amino] 4-methylbenzenesulfonate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17512-88-8 SDS

17512-88-8Relevant articles and documents

Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies

Semenov, Victor V.,Lichitsky, Boris V.,Komogortsev, Andrey N.,Dudinov, Arkady A.,Krayushkin, Mikhail M.,Konyushkin, Leonid D.,Atamanenko, Olga P.,Karmanova, Irina B.,Strelenko, Yuri A.,Shor, Boris,Semenova, Marina N.,Kiselyov, Alex S.

, p. 573 - 585 (2016/10/12)

A series of 3,7-diaryl-6,7-dihydroisothiazolo [4,5-b]pyridin-5(4H)-ones 8 and 9 was synthesized by multicomponent condensation of 3-aryl-5-isothiazolecarboxylic acid esters 4a–f with aromatic (or thienyl) aldehydes 7 and Meldrum's acid in an acidic medium

Synthesis, characterization and anti-proliferation activities of novel cyano oximino sulfonate esters

El-Faham, Ayman,Elnakdy, Yasser Abbas,El Gazzar, Sarah Abdou Mohamed,El-Rahman, Mohamed Mokbel Abd,Khattab, Sherine Nabil

, p. 373 - 378 (2014/04/17)

A series of novel cyano oximino sulfonate derivatives were prepared from the reaction of arylsulfonyl chloride with different cyanoacetamide-based oximes ranging from the simplest unsubstituted amide to analogues containing N-ethyl (mimicking the Oxyma template), N-piperidinyl and N-morpholinyl chains. In addition, the cyano oximes, N-hydroxybenzimidoyl cyanide and N-hydroxypicolinimidoyl cyanide were also used in the synthesis of the novel cyano oximino sulfonate derivatives. The structures of the prepared compounds were confirmed by 1H-NMR, 13C-NMR, and elemental analysis. The preliminary bioassays showed that some of the title compounds, such as 2-oxo-2-(piperidin-1-yl)-N-(tosyloxy)acetimidoyl cyanide (TsPipOx), N-(tosyloxy)benzimidoyl cyanide (TsPhOX), N-(naphthalen-2-ylsulfonyloxy)-2-oxo- 2-(piperidin-1-yl)acetimidoyl cyanide (NpsPipOx), 2-amino-N-(naphthalen-2- ylsulfonyloxy)-2-oxoacetimidoyl cyanide (NpsAmOx), N-(naphthalen-2- ylsulfonyloxy)benzimidoyl cyanide (NpsPhCN), and N-(naphthalen-2-ylsulfonyloxy) picolinimidoyl cyanide (NpsPyCN), showed anti-proliferation effect on the mouse fibroblast L929. The calculated IC50-values were ranging between 36.5 μg/mL and 0.235 mg/mL. However the anti-proliferation effects seem to be cytostatic rather than cytotoxic. The compounds only minimize the growth activity without completely killing the cells.

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