82424-58-6

Basic information

• Product Name: Methyl 4-aMino-3-phenylisothiazole-5-carboxylate
• Synonyms: Methyl 4-aMino-3-phenylisothiazole-5-carboxylate
• CAS NO: 82424-58-6
• Molecular Formula: C₁₁H₁₀N₂O₂S
• Molecular Weight: 234.2743
• Mol File: 82424-58-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 4-aMino-3-phenylisothiazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-aMino-3-phenylisothiazole-5-carboxylate(82424-58-6)
• EPA Substance Registry System: Methyl 4-aMino-3-phenylisothiazole-5-carboxylate(82424-58-6)

Safety Data

• Hazardous Substances Data: 82424-58-6(Hazardous Substances Data)

Usage

General Description

Methyl 4-amino-3-phenylisothiazole-5-carboxylate is a chemical compound with a molecular formula C11H10N2O2S. It is a white to off-white crystalline powder with a molecular weight of 242.27 g/mol. This chemical is a derivative of isothiazole and is used in the synthesis of pharmaceutical drugs and agricultural chemicals. It has also been studied for its potential antibacterial and antifungal properties. Methyl 4-amino-3-phenylisothiazole-5-carboxylate is an important intermediate in organic synthesis and has applications in the pharmaceutical and agricultural industries.

Upstream product

• 36659-88-8 2-hydroxyimino-2-phenylacetonitrile sodium 
• 17512-88-8 N-(tosyloxy)benzimidoyl cyanide 
• 2365-48-2 Methyl thioglycolate 
• 7541-02-8 (Z)-2-(hydroxyimino)-2-phenylacetonitrile 
• 7541-04-0 (Z)-N-(tosyloxy)benzimidoyl cyanide 
• 140-29-4 phenylacetonitrile 

Downstream Products

• 1235451-92-9 C₉H₈N₂S*ClH 
• 82424-75-7 3-Phenyl-4-aminoisothiazole-5-carboxylic acid 
• 1610354-28-3 4-(3-((3S,4R)-4-(3,4-difluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)ureido)-3-phenvlisothiazole-5-carboxamide 
• 68438-26-6 methyl 3-phenyl-1,2-thiazole-5-carboxylate 
• 110919-39-6 4-Chloro-3-phenyl-isothiazole-5-carboxylic acid methyl ester 
• 1265324-01-3 3-phenyl-4-(trifluoromethyl)isothiazole-5-carboxylic acid 
• 1265324-03-5 methyl 3-phenyl-4-(trifluoromethyl)isothiazole-5-carboxylate 
• 1265324-02-4 methyl 4-iodo-3-phenylisothiazole-5-carboxylate 

Relevant articles and documents

Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies

A series of 3,7-diaryl-6,7-dihydroisothiazolo [4,5-b]pyridin-5(4H)-ones 8 and 9 was synthesized by multicomponent condensation of 3-aryl-5-isothiazolecarboxylic acid esters 4a–f with aromatic (or thienyl) aldehydes 7 and Meldrum's acid in an acidic medium

SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS

Disclosed are compounds of Formula (I), or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: A is formula (II) Q is a substituted 5-membered monocyclic heteroaryl group; W is CH2, O, or NH; and R1, R2, R3, R4, R5, R6, m, n, t, and x are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.