82424-75-7

Upstream product

• 65237-13-0 ethyl 3-phenyl-4-aminoisothiazole-5-carboxylate 
• 140-29-4 phenylacetonitrile 
• 36659-88-8 2-hydroxyimino-2-phenylacetonitrile sodium 
• 17512-88-8 N-(tosyloxy)benzimidoyl cyanide 
• 82424-58-6 methyl 4-amino-3-phenylisothiazole-5-carboxylate 
• 5728-12-1 4-phenyl-[1,2,5]thiadiazol-3-ol 
• 105703-75-1 3-Phenyl-5-methyl-6H-isothiazolo<4.5-d>-1,3-oxazin-6-one 

Downstream Products

• 105703-75-1 3-Phenyl-5-methyl-6H-isothiazolo<4.5-d>-1,3-oxazin-6-one 
• 105689-22-3 3-Phenyl-4-aminoisothiazole 
• 1235451-92-9 C₉H₈N₂S*ClH 
• 105689-20-1 Methyl 3-Phenyl-4-acetoamidoisothiazole-5-carboxylate 
• 105689-21-2 3-Phenyl-4-acetoamidoisothiazole-5-carboxylic acid 
• 105689-19-8 3-Phenyl-5-methylisothiazolo<5,4-e>-3,4-dihydropyrimidin-4-one 

Relevant academic research and scientific papers

Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies

A series of 3,7-diaryl-6,7-dihydroisothiazolo [4,5-b]pyridin-5(4H)-ones 8 and 9 was synthesized by multicomponent condensation of 3-aryl-5-isothiazolecarboxylic acid esters 4a–f with aromatic (or thienyl) aldehydes 7 and Meldrum's acid in an acidic medium

Ring Transformation of 3-Hydroxy-1,2,5- and -1,2,4-thiadiazoles and -isothiazoles into Isothiazole , Thiazole and Thiophene Derivatives

Ring transformation of 3-hydroxy-1,2,5-thiadiazole (1), 3-hydroxy-1,2,4-thiadiazole (14), and 3-hydroxyisothiazole (18) by the reaction with acetic anhydride in the presence of DBU afforded isothiazoles 2-5 and 13, thiazoles 15 and 16 and thiophenes 21-25, respectively.The reaction of 1 with propionic anhydride gave isothiazole 13.The formation pathway of the products is mentioned.