82424-75-7

Basic information

• Product Name: 5-Isothiazolecarboxylic acid, 4-amino-3-phenyl-
• CAS NO: 82424-75-7
• Molecular Formula: C10H8N2O2S
• Molecular Weight: 220.252
• Mol File: 82424-75-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Isothiazolecarboxylic acid, 4-amino-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isothiazolecarboxylic acid, 4-amino-3-phenyl-(82424-75-7)
• EPA Substance Registry System: 5-Isothiazolecarboxylic acid, 4-amino-3-phenyl-(82424-75-7)

Safety Data

• Hazardous Substances Data: 82424-75-7(Hazardous Substances Data)

Upstream product

• 105703-75-1 3-Phenyl-5-methyl-6H-isothiazolo<4.5-d>-1,3-oxazin-6-one 
• 140-29-4 phenylacetonitrile 
• 36659-88-8 2-hydroxyimino-2-phenylacetonitrile sodium 
• 17512-88-8 N-(tosyloxy)benzimidoyl cyanide 
• 82424-58-6 methyl 4-amino-3-phenylisothiazole-5-carboxylate 
• 5728-12-1 4-phenyl-[1,2,5]thiadiazol-3-ol 
• 65237-13-0 ethyl 3-phenyl-4-aminoisothiazole-5-carboxylate 

Downstream Products

• 1235451-92-9 C₉H₈N₂S*ClH 
• 105689-20-1 Methyl 3-Phenyl-4-acetoamidoisothiazole-5-carboxylate 
• 105689-21-2 3-Phenyl-4-acetoamidoisothiazole-5-carboxylic acid 
• 105689-19-8 3-Phenyl-5-methylisothiazolo<5,4-e>-3,4-dihydropyrimidin-4-one 
• 105703-75-1 3-Phenyl-5-methyl-6H-isothiazolo<4.5-d>-1,3-oxazin-6-one 
• 105689-22-3 3-Phenyl-4-aminoisothiazole 

Relevant articles and documents

Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies

A series of 3,7-diaryl-6,7-dihydroisothiazolo [4,5-b]pyridin-5(4H)-ones 8 and 9 was synthesized by multicomponent condensation of 3-aryl-5-isothiazolecarboxylic acid esters 4a–f with aromatic (or thienyl) aldehydes 7 and Meldrum's acid in an acidic medium