17515-66-1

Usage

Uses

Used in Pharmaceutical Industry:
3-Carbethoxy-1,1,1-trifluorohexane-2,5-dione is used as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines. Its unique chemical properties make it a valuable component in the creation of complex organic molecules.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Carbethoxy-1,1,1-trifluorohexane-2,5-dione is utilized as an intermediate for the production of various agrochemicals, including pesticides and herbicides. Its role in these applications aids in enhancing crop protection and agricultural productivity.
Used as a Solvent in Chemical Processes:
3-Carbethoxy-1,1,1-trifluorohexane-2,5-dione is employed as a solvent in a range of chemical processes due to its ability to dissolve a variety of substances. This makes it a versatile component in the chemical industry, facilitating reactions and improving process efficiency.

InChI:InChI=1/C55H112O3/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52-56-55(57-53-50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)58-54-51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h55H,4-54H2,1-3H3

Upstream product

• 78-95-5 chloroacetone 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 383-63-1 ethyl trifluoroacetate, 
• 4749-28-4 2-nitropropene 

Downstream Products

• 17515-73-0 ethyl 5-methyl-2-trifluoromethylfuran-3-carboxylate 
• 1609112-61-9 C₁₃H₁₀F₃NO₂ 
• 1609113-20-3 C₁₄H₁₀F₃NO₄ 
• 17515-75-2 2-methyl-5-(trifluoromethyl)furan 

Relevant academic research and scientific papers

Reaction of ethyl 4,4,4-trifluoroacetoacetate enolate with 3-bromo-1,1,1-trifluoroacetone: Synthesis of 2,4-bis (trifluoromethyl) furan

The potassium enolate of ethyl 4,4,4-trifluoroacetoacetate 1 reacts with 3-bromo-1,1,1-trifluoroacetone 2 in DMSO solution to yield three products. Ethyl 2,4-bis(trifluoromethyl)-4-hydroxydihydro-3-furoate 3 is generated via C-acylation. The hydrated trifluoromethyl ketone 4 is formed by O-alkylation and 4 reacts further with 2 to give the di-O-alkylated ketone hydrate 5. Compound 3 undergoes dehydration to the furan derivative 6 on reaction with Ac2O-ZnCl2.

Discovery of Novel Inhibitors of Uridine Diphosphate- N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients

Pseudomonas aeruginosa is of major concern for cystic fibrosis patients where this infection can be fatal. With the emergence of drug-resistant strains, there is an urgent need to develop novel antibiotics against P. aeruginosa. MurB is a promising target

PYRROL-1 -YL BENZOIC ACID DERIVATES USEFUL AS MYC INHIBITORS

The present invention provides compounds of Formula (I-A), (I-B), and (I-C), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting Myc (e.g., c-Myc) activity. The p

AMINOETHANOL DERIVATIVES

The present invention provides a pharmaceutical agent having cholesteryl ester transfer protein inhibitory action and useful as a blood lipid lowering agent and the like. The present invention relates to a compound represented by the formula wherein Ar1 is an aromatic ring group optionally having substituents, Ar2 is an aromatic ring group having substituents, OR'' is an optionally protected hydroxyl group, R is an acyl group, R' is a hydrogen atom or a hydrocarbon group optionally having substituents, or a salt thereof, and a pharmaceutical composition containing a compound of the formula (I) or a salt thereof or a prodrug thereof.